Imaging patterns of intraductal papillary mucinous neoplasms of the pancreas: An illustrated discussion of the International Consensus Guidelines for the Management of IPMN Journal Article
| Authors: | Campbell, N. M.; Katz, S. S.; Escalon, J. G.; Do, R. K. |
| Article Title: | Imaging patterns of intraductal papillary mucinous neoplasms of the pancreas: An illustrated discussion of the International Consensus Guidelines for the Management of IPMN |
| Abstract: | Intraductal papillary mucinous neoplasms (IPMN) are being diagnosed with increasing frequency, necessitating an algorithm to help stratify patients into low- and high-risk groups, for follow-up versus more invasive evaluation. New evidence concerning their natural history and overall risk of malignancy has emerged since the 2006 International Association of Pancreatology consensus guidelines, prompting an update in 2012, that distinguishes radiologic ‘worrisome features’ from ‘high-risk stigmata’. The aim of this article is to illustrate, with case examples, the variable imaging patterns of IPMN and how their radiologic features, such as cyst size and mural nodules, are interpreted in the context of the new 2012 guidelines. The 2012 and 2006 guidelines will be compared and discussed with reference to additional studies that have since been published. Despite these guidelines, lingering uncertainty remains about the natural history of IPMN, a source of unease to both radiologists and referring clinicians alike, mandating further refinement of clinical and radiologic parameters predictive of malignancy. Emerging data regarding the risk of extrapancreatic malignancy, as well as synchronous or metachronous pancreatic ductal adenocarcinoma remote in location from a branch duct IPMN are also reviewed. With the expanding research and evolving understanding of this clinicopathologic entity across the globe, radiologists will continue to play an important role in the management of patients with IPMN. |
| Keywords: | clinical feature; histopathology; review; cancer patient; nuclear magnetic resonance imaging; pancreaticoduodenectomy; pancreas; disease association; consensus; computer assisted tomography; tumor volume; differential diagnosis; intraductal papillary mucinous tumor; pancreas cyst; practice guideline; diagnostic imaging; risk factor; high risk patient; radiologist; contrast enhancement; chronic pancreatitis; pancreas duct; clinical evaluation; ionizing radiation; pancreas adenocarcinoma; pancreatic cancer; meta analysis; predictive value; pancreas disease; endoscopic echography; uncertainty; diagnostic test accuracy study; radiological parameters; pancreatic neoplasm; obstructive jaundice; ipmn; cancer prognosis; human; priority journal; contrast enhanced computed tomography; intraductal papillary mucinous neoplasm of the pancreas; pancreatic cystic lesion; pancreas dilatation |
| Journal Title: | Abdominal Imaging |
| Volume: | 40 |
| Issue: | 3 |
| ISSN: | 0942-8925 |
| Publisher: | Springer |
| Date Published: | 2015-03-01 |
| Start Page: | 663 |
| End Page: | 677 |
| Language: | English |
| DOI: | 10.1007/s00261-014-0236-4 |
| PROVIDER: | scopus |
| PUBMED: | 25219664 |
| DOI/URL: | |
| Notes: | Export Date: 2 March 2015 -- Source: Scopus |
Altmetric
Citation Impact
Related MSK Work