Authors: | Ferlito, A.; Shaha, A. R.; Rinaldo, A. |
Article Title: | The incidence of lymph node micrometastases in patients pathologically staged N0 in cancer of oral cavity and oropharynx |
Abstract: | The presence of nodal metastasis in head and neck cancer is an important prognostic factor and crucial in making critical decisions regarding postoperative radiation treatment and follow up. The final documentation of nodal metastasis is still based on routine histopathological evaluation of the lymph nodes in the neck. The newer technologies including immunohistochemistry, molecular analysis and subserial sectioning may increase the detection of lymph node micrometastases in patients pathologically staged N0 in cancer of oral cavity and oropharynx. © 2002 Elsevier Science Ltd. All rights reserved. |
Keywords: | immunohistochemistry; histopathology; review; cancer patient; cancer staging; lymph node metastasis; cancer diagnosis; cancer incidence; lymph nodes; lymphatic metastasis; neoplasm staging; sensitivity and specificity; sentinel lymph node biopsy; mouth carcinoma; mouth neoplasms; oral cavity; genetic markers; oropharynx carcinoma; oropharyngeal neoplasms; staining and labeling; oropharynx; occult cancer; humans; human; priority journal; occult metastases; occult micrometastases |
Journal Title: | Oral Oncology |
Volume: | 38 |
Issue: | 1 |
ISSN: | 1368-8375 |
Publisher: | Elsevier Inc. |
Date Published: | 2002-01-01 |
Start Page: | 3 |
End Page: | 5 |
Language: | English |
DOI: | 10.1016/s1368-8375(01)00037-9 |
PUBMED: | 11755814 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Export Date: 14 November 2014 -- Source: Scopus |