3-Alkyloxycyclobutanones as useful synthons for heterocycle and carbocycle synthesis Journal Article


Authors: Chen, S.; Shan, G.; Nie, P.; Rao, Y.
Article Title: 3-Alkyloxycyclobutanones as useful synthons for heterocycle and carbocycle synthesis
Abstract: Substituted 3-alkyloxycyclobutanones are highly valuable intermediates in organic synthesis, which demonstrate interesting and rich reactivity in different types of reactions due to the strain energy. Under Lewis acid catalysis, 3-alkyloxycyclobutanones can form zwitterionic intermediates and participate in a series of cycloaddition reactions as three- or four-carbon synthons. This Focus Review will mainly discuss formal [4+2], [3+2], and [3+3] annulations as well as other types of transformations with 3-alkyloxycyclobutanones.
Keywords: cycloaddition; lewis acids; heterocycles; 3-alkyloxycyclobutanones; zwitterions
Journal Title: Asian Journal of Organic Chemistry
Volume: 4
Issue: 1
ISSN: 2193-5807
Publisher: Wiley V C H Verlag Gmbh  
Date Published: 2015-01-01
Start Page: 16
End Page: 26
Language: English
DOI: 10.1002/ajoc.201402200
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 2 February 2015 -- Source: Scopus
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  1. Shi Chen
    10 Chen