Studies directed to the total synthesis of ET 743 and analogues thereof: An expeditious route to the ABFGH subunit Journal Article
| Authors: | Zhou, B.; Guo, J.; Danishefsky, S. J. |
| Article Title: | Studies directed to the total synthesis of ET 743 and analogues thereof: An expeditious route to the ABFGH subunit |
| Abstract: | (matrix presented) In model studies directed to the total synthesis of Et743, a strategic S-C bond formation in systems 26 and 27 was demonstrated. It was further shown that Pictet-Spengler cyclization leading to spiro product 33 exhibits very high stereoselection. |
| Keywords: | animal; animals; alkylating agent; chemistry; antineoplastic agents, alkylating; conformation; trabectedin; molecular conformation; synthesis; stereoisomerism; spiro compound; spiro compounds; indicators and reagents; lactones; isoquinoline derivative; dioxoles; isoquinolines; lactone; tetrahydroisoquinolines; dyes, reagents, indicators, markers and buffers; tetrahydroisoquinoline derivative; urochordata; 1,3 dioxolane derivative; article |
| Journal Title: | Organic Letters |
| Volume: | 4 |
| Issue: | 1 |
| ISSN: | 1523-7060 |
| Publisher: | American Chemical Society |
| Date Published: | 2002-01-10 |
| Start Page: | 43 |
| End Page: | 46 |
| Language: | English |
| DOI: | 10.1021/ol016844k |
| PUBMED: | 11772086 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
