Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: Case report and review of a controversial therapy Journal Article


Authors: Sanders, S.; Busam, K. J.; Halpern, A. C.; Nehal, K. S.
Article Title: Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: Case report and review of a controversial therapy
Abstract: BACKGROUND. Use of intralesional corticosteroids in the management of keratoacanthomas has been reported in older literature. Yet this therapy is no longer a commonly considered treatment option. OBJECTIVE. To report management of a therapeutically challenging patient with multiple eruptive keratoacanthomas with intralesional corticosteriod treatment to revive awareness of this treatment option. METHODS. A 55-year-old female with frequent episodes of multiple eruptive keratoacanthomas was treated with intralesional corticosteroids and methotrexate. RESULTS. Intralesional corticosteroids successfully treated eruptive keratoacanthomas with complete regression and minimal scarring within 2-4 weeks. CONCLUSION. Despite its limitations, intralesional corticosteroids may have a role in the treatment of select keratoacanthomas.
Keywords: adult; treatment outcome; middle aged; case report; fluorouracil; interferon; side effect; methotrexate; morbidity; drug effect; biopsy; prednisolone; remission; scar formation; bleomycin; skin disease; methicillin resistant staphylococcus aureus; lidocaine; vancomycin; corticosteroid; tetracycline; retinoid; meticillin; leg; glucocorticoids; keratoacanthoma; dermatologic agents; triamcinolone; arm; bipolar disorder; triamcinolone acetonide; injections, intralesional; dicloxacillin; humans; human; female; priority journal; article; hydrocortisone acetate; lithium carbonate; triamcinolone diacetate; triamcinolone hexacetonide
Journal Title: Dermatologic Surgery
Volume: 28
Issue: 10
ISSN: 1076-0512
Publisher: Lippincott Williams & Wilkins  
Date Published: 2002-10-01
Start Page: 954
End Page: 958
Language: English
DOI: 10.1046/j.1524-4725.2002.02069.x
PUBMED: 12410683
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Allan C Halpern
    396 Halpern
  2. Kishwer S Nehal
    278 Nehal
  3. Klaus J Busam
    688 Busam