Partial nephrectomy: The rationale for expanding the indications Journal Article
| Authors: | Russo, P.; Goetzl, M.; Simmons, R.; Katz, J.; Motzer, R.; Reuter, V. |
| Article Title: | Partial nephrectomy: The rationale for expanding the indications |
| Abstract: | Background: We report preliminary results of partial nephrectomy for renal tumors of ≥4 cm in 39 patients with the intent of extending the indications for kidney-sparing surgery. Methods: From July 1989 to October 2001, 39 patients underwent a partial nephrectomy for renal cortical tumors >4 cm in maximum diameter. Fourteen (36%) had the procedure performed for essential reasons, and 25 (64%) had an elective kidney-sparing operation. We evaluated tumor location and histology, perioperative renal function, and postoperative complications. Results: There were 20 conventional clear-cell (51%), 13 papillary (33%), 4 chromophobe (10%), and 3 oncocytomas (8%) with a median tumor size of 5 cm. After a median follow-up of 13 months, 36 patients had no evidence of disease, 1 patient had died as a result of other causes, and 2 patients who had essential operations were alive with disease. Twenty-three patients (70%) maintained normal postoperative renal function. Of six patients with moderate preoperative renal dysfunction, five (83%) had no change in postoperative renal function and only one patient required short-term dialysis. Conclusions: With careful patient selection, partial nephrectomy can be effectively used to treat patients with renal cortical tumors >4 cm in diameter. The benefits of this approach include the effective local tumor control while at the same time preserving maximum renal function. |
| Keywords: | adult; clinical article; controlled study; aged; aged, 80 and over; disease-free survival; middle aged; survival rate; patient selection; cancer staging; neoplasm staging; treatment indication; oncocytoma; kidney neoplasms; nephrectomy; partial nephrectomy; kidney tumor; cancer size; new york city; clear cell carcinoma; papillary carcinoma; chromophobe adenoma; renal tumors; tumor staging; humans; human; male; female; article; kidney-sparing surgery |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 9 |
| Issue: | 7 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 2002-08-01 |
| Start Page: | 680 |
| End Page: | 687 |
| Language: | English |
| DOI: | 10.1245/aso.2002.9.7.680 |
| PUBMED: | 12167583 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
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