Time trends in organ position and volume in patients receiving prostate three-dimensional conformal radiotherapy Journal Article


Authors: Mechalakos, J. G.; Mageras, G. S.; Zelefsky, M. J.; Lyass, O.; Van Herk, M.; Kooy, H. M.; Leibel, S. A.; Ling, C. C.
Article Title: Time trends in organ position and volume in patients receiving prostate three-dimensional conformal radiotherapy
Abstract: Using multiple computed tomography (CT) scans, 50 patients undergoing prostate radiotherapy were tested for clinically significant time trends in the target and surrounding critical structures. Significant trends were observed toward increasing bladder volume and increasing bowel-to-planning target volume separation; however, no trends were observed in the prostate, seminal vesicles, or rectum. The subset of patients undergoing hormone therapy was also tested and did not independently exhibit any significant time trends. © 2002 Elsevier Science Ireland Ltd. All rights reserved.
Keywords: clinical article; controlled study; neoadjuvant therapy; tomography, x-ray computed; time; prostatic neoplasms; prostate; imaging, three-dimensional; urinary bladder; androgen antagonists; hormonal therapy; radiotherapy, conformal; hormone; seminal vesicle; body posture; patient positioning; computer assisted radiotherapy; hormone therapy; prostate carcinoma; rectum; organ motion; bladder capacity; prone position; humans; human; male; priority journal; article; intestine motility; time trend
Journal Title: Radiotherapy and Oncology
Volume: 62
Issue: 3
ISSN: 0167-8140
Publisher: Elsevier Inc.  
Date Published: 2002-03-01
Start Page: 261
End Page: 265
Language: English
DOI: 10.1016/s0167-8140(01)00466-2
PUBMED: 12175556
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Michael J Zelefsky
    754 Zelefsky
  2. Steven A Leibel
    252 Leibel
  3. Gikas S Mageras
    277 Mageras
  4. C Clifton Ling
    331 Ling