Fine-needle aspiration biopsy of axillary lymph nodes Journal Article


Authors: Jaffer, S.; Zakowski, M.
Article Title: Fine-needle aspiration biopsy of axillary lymph nodes
Abstract: To assess the efficacy of fine-needle aspiration biopsy (FNAB) of axillary lymph nodes (ALN), we retrospectively analyzed 140 FNAB of ALN at Memorial Sloan-Kettering Cancer Center, examining technique and cytologic-histologic correlation. Of the 140 FNAB, 124 were performed by the conventional method and 16 by ultrasound guidance (USG). The diagnoses included: unsatisfactory, 20; negative, 38; positive, 72; suspicious, 6; and indeterminate, 4. Positive diagnoses included: carcinoma, 44.4%; melanoma, 43.0%; lymphoma, 5.6%; sarcoma, 5.6%; and mesothelioma, 1.4%; one of which was false-positive, attributed to misinterpretation. All indeterminate and most false-negative cases were due to lymphoproliferative conditions. The sensitivity and specificity of FNAB of ALN were 94.7% and 97.1% and the adequacy rate was 85.7%. The sensitivity, specificity, and adequacy rates of USG FNAB were 100%. Our study shows that FNAB of ALN is an excellent method for diagnosing reactive conditions as well as neoplasms. © 2002 Wiley-Liss, Inc.
Keywords: adolescent; adult; human tissue; aged; aged, 80 and over; middle aged; major clinical study; lymph nodes; lymphatic metastasis; diagnostic accuracy; sensitivity and specificity; sentinel lymph node biopsy; neoplasms; reproducibility of results; cytology; melanoma; histology; ultrasound; sarcoma; axillary lymph node; correlation analysis; diagnostic errors; biopsy, needle; lymphoma; carcinoma; mesothelioma; lymphoproliferative disease; axilla; aspiration biopsy; technique; axillary lymph nodes; fine-needle aspiration biopsy; humans; human; male; female; priority journal; article
Journal Title: Diagnostic Cytopathology
Volume: 26
Issue: 2
ISSN: 8755-1039
Publisher: Wiley Liss  
Date Published: 2002-02-01
Start Page: 69
End Page: 74
Language: English
DOI: 10.1002/dc.10051
PUBMED: 11813321
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Shabnam Jaffer
    3 Jaffer
  2. Maureen F Zakowski
    289 Zakowski