Pythium insidiosum pleuropericarditis complicating pneumonia in a child with leukemia Journal Article
| Authors: | Heath, J. A.; Kiehn, T. E.; Brown, A. E.; LaQuaglia, M. P.; Steinherz, L. J.; Bearman, G.; Wong, M.; Steinherz, P. G. |
| Article Title: | Pythium insidiosum pleuropericarditis complicating pneumonia in a child with leukemia |
| Abstract: | We describe a 12-year-old boy with acute myeloid leukemia who developed pleuropericarditis while he was neutropenic and was receiving intravenously administered antibiotic and antifungal therapy for pneumonia. A KOH preparation of the purulent material from an extensive diagnostic and therapeutic pleuropericardial drainage procedure revealed multiple irregularly septate hyphae, and cultures yielded the organism Pythium insidiosum. After completing a 12-month course of intravenously administered liposomal amphotericin B (AmBisome; Fujisawa Healthcare) and itraconazole, the patient remained alive, in clinical remission, and symptom free. |
| Keywords: | child; acute granulocytic leukemia; case report; antifungal agent; pneumonia; microbiology; pericarditis; amphotericin b; leukemia, myelocytic, acute; antibiotics, antifungal; humans; human; male; article; pythium |
| Journal Title: | Clinical Infectious Diseases |
| Volume: | 35 |
| Issue: | 6 |
| ISSN: | 1058-4838 |
| Publisher: | Oxford University Press |
| Date Published: | 2002-09-15 |
| Start Page: | e60 |
| End Page: | e64 |
| Language: | English |
| PUBMED: | 12203186 |
| PROVIDER: | scopus |
| DOI: | 10.1086/342303 |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
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