Health technology assessment in evolution - focal therapy in localised prostate cancer Journal Article
| Authors: | Valerio, M.; Emberton, M.; Barret, E.; Eberli, D.; Eggener, S. E.; Ehdaie, B.; Jichlinski, P.; Ward, J. F.; Ahmed, H. U. |
| Article Title: | Health technology assessment in evolution - focal therapy in localised prostate cancer |
| Abstract: | Focal therapy in prostate cancer aims to treat only the part of the gland harboring clinically significant disease while preserving the rest of the tissue. This approach may substantially reduce treatment-related toxicity without compromising disease control outcomes. Short-to medium-term functional and oncological results in prospective interventional studies are promising, but comparative effectiveness research against standard of care is required to incorporate focal therapy among standard options. In this review, we discuss the actual stage of assessment and results of sources of energy commonly used to deliver focal therapy. We also provide our viewpoint on how the field will evolve in the near future. |
| Keywords: | mortality; treatment; prostate cancer; cryoablation; minimally invasive; recommendations; follow-up; metaanalysis; focal therapy; intensity-focused ultrasound; screening trial; assisted radical prostatectomy; randomized prostate; health technology assessment; tissue-preserving approaches; surgical innovation |
| Journal Title: | Expert Review of Anticancer Therapy |
| Volume: | 14 |
| Issue: | 11 |
| ISSN: | 1473-7140 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2014-11-01 |
| Start Page: | 1359 |
| End Page: | 1367 |
| Language: | English |
| ACCESSION: | WOS:000344770200014 |
| DOI: | 10.1586/14737140.2014.932692 |
| PROVIDER: | wos |
| PUBMED: | 24965212 |
| Notes: | Review -- Source: Wos |
