Psychopharmacology in cancer Journal Article


Authors: Thekdi, S. M.; Trinidad, A.; Roth, A.
Article Title: Psychopharmacology in cancer
Abstract: Depression, anxiety, delirium, and other psychiatric symptoms are highly prevalent in the cancer setting, and pharmacological intervention is an important component in the overall psychosocial care of the patient. Psychopharmacology is also used as a primary or adjuvant treatment for the management of cancer-related symptoms stemming from the disease itself and/or its treatment, including sleep disturbance, loss of appetite, neuropathic pain, nausea, fatigue, and hot flashes. Psychiatrists, oncologists, and palliative care physicians working as members of a multidisciplinary team have the opportunity to target multiple symptoms that negatively affect a patient’s quality of life with the strategic use of psychotropic medications when deemed appropriate. This article aims to review the indications for use of antidepressants, psychostimulants, anxiolytics, antipsychotics, and mood stabilizers in oncology. An updated review of the relevant literature is discussed and referenced in each section.
Keywords: drug tolerability; fatigue; review; drug efficacy; drug potentiation; drug safety; hypertension; cancer patient; anorexia; neoplasm; unindexed drug; quality of life; breast cancer; nausea; aripiprazole; chlorpromazine; haloperidol; lorazepam; methylphenidate; modafinil; olanzapine; quetiapine; delirium; bedtime dosage; cancer pain; dizziness; confusion; insomnia; depression; disease severity; drug mechanism; head and neck cancer; morning dosage; drug response; psycho-oncology; antidepressant agent; benzodiazepine derivative; neuroleptic agent; tamoxifen; mirtazapine; anxiety; hot flush; drug metabolism; respiration depression; motor dysfunction; hiccup; alprazolam; venlafaxine; drug contraindication; clonazepam; paroxetine; mood disorder; valproic acid; psychologic assessment; amfebutamone; psychostimulant agent; serotonin uptake inhibitor; randomized controlled trial (topic); dexamphetamine; armodafinil; trazodone; zolpidem; psychopharmacology; increased appetite; diazepam; lithium; cancer; human; cancer-related symptoms; temazepam; endoxifen
Journal Title: Current Psychiatry Reports
Volume: 17
Issue: 1
ISSN: 1523-3812
Publisher: Springer  
Date Published: 2014-01-01
Start Page: 529
Language: English
DOI: 10.1007/s11920-014-0529-x
PROVIDER: scopus
PUBMED: 25417593
DOI/URL:
Notes: Export Date: 2 January 2015 -- 10 page article -- Source: Scopus
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  1. Andrew J Roth
    104 Roth
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