Lipid-based patterning of the immunological synapse Journal Article


Author: Huse, M.
Article Title: Lipid-based patterning of the immunological synapse
Abstract: The immunological synapse controls T-lymphocyte function by polarizing effector responses towards the antigen-presenting cell. In this review, I discuss the molecular pathways required for synapse assembly, focusing on the central roles played by lipid second-messenger signalling.
Keywords: signal transduction; review; t lymphocyte; actin; lipid; cell polarity; f actin; microtubule; antigen presenting cell; diacylglycerol; centrosome; second messenger; t-cell; immunological synapse; protein kinase c (pkc); inositol phosphate
Journal Title: Biochemical Society Transactions
Volume: 42
Issue: 6
ISSN: 0300-5127
Publisher: Portland Press Ltd  
Date Published: 2014-12-01
Start Page: 1506
End Page: 1511
Language: English
DOI: 10.1042/bst20140191
PROVIDER: scopus
PUBMED: 25399561
PMCID: PMC4993624
DOI/URL:
Notes: Export Date: 2 January 2015 -- Source: Scopus
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  1. Morgan Huse
    36 Huse