Lipid-based patterning of the immunological synapse Journal Article
| Author: | Huse, M. |
| Article Title: | Lipid-based patterning of the immunological synapse |
| Abstract: | The immunological synapse controls T-lymphocyte function by polarizing effector responses towards the antigen-presenting cell. In this review, I discuss the molecular pathways required for synapse assembly, focusing on the central roles played by lipid second-messenger signalling. |
| Keywords: | signal transduction; review; t lymphocyte; actin; lipid; cell polarity; f actin; microtubule; antigen presenting cell; diacylglycerol; centrosome; second messenger; t-cell; immunological synapse; protein kinase c (pkc); inositol phosphate |
| Journal Title: | Biochemical Society Transactions |
| Volume: | 42 |
| Issue: | 6 |
| ISSN: | 0300-5127 |
| Publisher: | Portland Press Ltd |
| Date Published: | 2014-12-01 |
| Start Page: | 1506 |
| End Page: | 1511 |
| Language: | English |
| DOI: | 10.1042/bst20140191 |
| PROVIDER: | scopus |
| PUBMED: | 25399561 |
| PMCID: | PMC4993624 |
| DOI/URL: | |
| Notes: | Export Date: 2 January 2015 -- Source: Scopus |
