Cement salvage of instrumentation-associated vertebral fractures Journal Article


Authors: Xu, R.; O'connor, K.; Krol, G.; Yamada, Y.; Bilsky, M.; Laufer, I.; Lis, E.
Article Title: Cement salvage of instrumentation-associated vertebral fractures
Abstract: BACKGROUND AND PURPOSE: Spinal instrumentation plays a key role in the treatment of spinal instability in patients with metastatic tumors. Poor bone quality, radiation, and diffuse osseous tumor involvement present significant challenges to spinal stabilization with instrumentation and occasionally result in postinstrumentation compression fractures. Vertebral cement augmentation has been effective in the treatment of painful tumor-related compression fractures. Our objective was to describe cement augmentation options in the treatment of vertebral compression fractures associated with spinal instrumentation in patients with metastatic tumors. MATERIALS AND METHODS: Patients who underwent percutaneous vertebral cement augmentation in the treatment of instrumentation-associated vertebral compression fractures between 2005 and 2011 were included in the analysis. Only fractures that occurred within the construct or at an adjacent level were included. The change in Visual Analog Scale and need for further surgery were analyzed. RESULTS: Eleven patients met the inclusion criteria, with 8 tumors located in the thoracic spine and 3 tumors in the lumbar spine. The median time between instrumented surgery and vertebral augmentation was 5 months (1-48 months) and the median follow-up after cement augmentation was 24 months (4-59 months). A total of 22 vertebrae that were either within or immediately adjacent to the surgical instrumentation underwent vertebral augmentation. All patients reported a decrease in their pain scores (mean decrease: 6 Visual Analog Scale points; P < .003). One patient required reoperation after cement augmentation. None of the patients experienced vertebral cement augmentation-related complications. CONCLUSIONS: Vertebral cement augmentation represents a safe and effective treatment option in patients with recurrent or progressive back pain and instrumentation-associated vertebral compression fractures.
Keywords: adult; clinical article; aged; salvage therapy; follow up; tumor localization; backache; decompression surgery; reoperation; visual analog scale; spine metastasis; bone cement; kyphoplasty; lumbar spine; thoracic spine; compression fracture; spine fracture; human; male; female; article; spine fixation device
Journal Title: American Journal of Neuroradiology
Volume: 35
Issue: 11
ISSN: 0195-6108
Publisher: American Society of Neuroradiology  
Date Published: 2014-11-01
Start Page: 2197
End Page: 2201
Language: English
DOI: 10.3174/ajnr.A4037
PROVIDER: scopus
PUBMED: 25059695
PMCID: PMC7965171
DOI/URL:
Notes: Export Date: 2 January 2015 -- Source: Scopus
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MSK Authors
  1. Eric Lis
    138 Lis
  2. Yoshiya Yamada
    479 Yamada
  3. Mark H Bilsky
    319 Bilsky
  4. George Krol
    86 Krol
  5. Ilya Laufer
    146 Laufer
  6. Ran Xu
    5 Xu