Variable risk of second primary malignancy in multiple myeloma patients of different ethnic subgroups Journal Article


Authors: Ailawadhi, S.; Swaika, A.; Razavi, P.; Yang, D.; Chanan-Khan, A.
Article Title: Variable risk of second primary malignancy in multiple myeloma patients of different ethnic subgroups
Abstract: Second primary malignancies (SPMs) among multiple myeloma (MM) patients have been reported with an estimated incidence varying from 1 to 15%. We have previously reported that significant disparity exists in MM survival across patients of different ethnicities. We undertook a Surveillance Epidemiology and End Results-based analysis to describe the incidence of SPMs among MM patients of different ethnicities, to explore the variable impact that SPMs might have on MM outcomes of patients across racial subgroups. We found that the risk of developing SPMs among MM patients is variable depending on the patient's ethnic background. This warrants further exploration of the impact of SPMs on outcomes of MM patients across different racial subgroups, especially in the form of prospective data collection and analyses.
Keywords: cancer survival; lenalidomide; patterns; stem-cell transplantation; united-states; racial disparities; acute-leukemia; monoclonal; myelodysplastic; syndromes; gammopathy; undetermined significance mgus
Journal Title: Blood Cancer Journal
Volume: 4
ISSN: 2044-5385
Publisher: Nature Publishing Group  
Date Published: 2014-09-05
Start Page: e243
Language: English
ACCESSION: WOS:000343202800001
DOI: 10.1038/bcj.2014.63
PROVIDER: wos
PMCID: PMC4183772
PUBMED: 25192415
Notes: Article -- e243 -- Source: Wos
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  1. Pedram Razavi
    144 Razavi