PTEN and p53: Who will get the upper hand? Journal Article
| Authors: | Trotman, L. C.; Pandolfi, P. P. |
| Article Title: | PTEN and p53: Who will get the upper hand? |
| Abstract: | Mutations of PTEN and p53 are very frequent, yet often mutually exclusive due to functional interdependence of the proteins and, according to a new study, the most intimate possible interaction: direct binding. |
| Keywords: | signal transduction; gene mutation; genetics; note; protein function; mouse; animal; metabolism; mouse mutant; animals; mice; mice, knockout; cell cycle; breast cancer; phosphatase; protein protein interaction; protein binding; protein p53; physiology; homozygosity; tumor suppressor gene; tumor suppressor proteins; phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase; pten phosphohydrolase; tumor suppressor protein p53; short survey; tumor suppressor protein; phosphoric monoester hydrolases; pten protein, human; autosomal dominant disorder; genes, tumor suppressor; cross linking; humans; human; priority journal |
| Journal Title: | Cancer Cell |
| Volume: | 3 |
| Issue: | 2 |
| ISSN: | 1535-6108 |
| Publisher: | Cell Press |
| Date Published: | 2003-02-01 |
| Start Page: | 97 |
| End Page: | 99 |
| Language: | English |
| DOI: | 10.1016/s1535-6108(03)00022-9 |
| PUBMED: | 12620402 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 25 September 2014 -- Source: Scopus |
