PTEN and p53: Who will get the upper hand? Journal Article


Authors: Trotman, L. C.; Pandolfi, P. P.
Article Title: PTEN and p53: Who will get the upper hand?
Abstract: Mutations of PTEN and p53 are very frequent, yet often mutually exclusive due to functional interdependence of the proteins and, according to a new study, the most intimate possible interaction: direct binding.
Keywords: signal transduction; gene mutation; genetics; note; protein function; mouse; animal; metabolism; mouse mutant; animals; mice; mice, knockout; cell cycle; breast cancer; phosphatase; protein protein interaction; protein binding; protein p53; physiology; homozygosity; tumor suppressor gene; tumor suppressor proteins; phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase; pten phosphohydrolase; tumor suppressor protein p53; short survey; tumor suppressor protein; phosphoric monoester hydrolases; pten protein, human; autosomal dominant disorder; genes, tumor suppressor; cross linking; humans; human; priority journal
Journal Title: Cancer Cell
Volume: 3
Issue: 2
ISSN: 1535-6108
Publisher: Cell Press  
Date Published: 2003-02-01
Start Page: 97
End Page: 99
Language: English
DOI: 10.1016/s1535-6108(03)00022-9
PUBMED: 12620402
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 25 September 2014 -- Source: Scopus
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  1. Lloyd Christopher Trotman
    11 Trotman