Oxaliplatin-based combined-modality therapy for rectal cancer Journal Article


Author: Minsky, B. D.
Article Title: Oxaliplatin-based combined-modality therapy for rectal cancer
Abstract: There are two conventional treatments for clinically resectable rectal cancer. The first is surgery, and, if the tumor is T3 and/or NI-2, this is followed by postoperative combined-modality therapy. The second, for patients with ultrasound T3 or clinical T4 disease, is preoperative combined-modality therapy followed by surgery and postoperative chemotherapy. In this review, the results of these approaches as well as novel combined-modality approaches using oxaliplatin-based regimens will be presented. © 2003 Elsevier Inc. All rights reserved.
Keywords: cancer survival; treatment outcome; clinical trial; cancer recurrence; fluorouracil; cancer combination chemotherapy; multimodality cancer therapy; side effect; antineoplastic agents; conference paper; capecitabine; cancer adjuvant therapy; cancer radiotherapy; postoperative care; preoperative care; radiation dose; chemotherapy, adjuvant; combined modality therapy; radiotherapy, adjuvant; antineoplastic agent; neoplasm staging; preoperative evaluation; tumor volume; continuous infusion; high risk patient; irinotecan; folinic acid; gefitinib; preoperative treatment; acute toxicity; oxaliplatin; rectal neoplasms; rectum cancer; organoplatinum compounds; clinical trials; rectum surgery; anal canal; anus sphincter; raltitrexed; uft; humans; prognosis; human; priority journal
Journal Title: Seminars in Oncology
Volume: 30
Issue: 4 Suppl.15
ISSN: 0093-7754
Publisher: Elsevier Inc.  
Date Published: 2003-08-01
Start Page: 26
End Page: 33
Language: English
PUBMED: 14523792
PROVIDER: scopus
DOI: 10.1016/S0093-7754(03)00402-0
DOI/URL:
Notes: Export Date: 25 September 2014 -- Source: Scopus
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  1. Bruce Minsky
    306 Minsky