Author: | Minsky, B. D. |
Article Title: | Oxaliplatin-based combined-modality therapy for rectal cancer |
Abstract: | There are two conventional treatments for clinically resectable rectal cancer. The first is surgery, and, if the tumor is T3 and/or NI-2, this is followed by postoperative combined-modality therapy. The second, for patients with ultrasound T3 or clinical T4 disease, is preoperative combined-modality therapy followed by surgery and postoperative chemotherapy. In this review, the results of these approaches as well as novel combined-modality approaches using oxaliplatin-based regimens will be presented. © 2003 Elsevier Inc. All rights reserved. |
Keywords: | cancer survival; treatment outcome; clinical trial; cancer recurrence; fluorouracil; cancer combination chemotherapy; multimodality cancer therapy; side effect; antineoplastic agents; conference paper; capecitabine; cancer adjuvant therapy; cancer radiotherapy; postoperative care; preoperative care; radiation dose; chemotherapy, adjuvant; combined modality therapy; radiotherapy, adjuvant; antineoplastic agent; neoplasm staging; preoperative evaluation; tumor volume; continuous infusion; high risk patient; irinotecan; folinic acid; gefitinib; preoperative treatment; acute toxicity; oxaliplatin; rectal neoplasms; rectum cancer; organoplatinum compounds; clinical trials; rectum surgery; anal canal; anus sphincter; raltitrexed; uft; humans; prognosis; human; priority journal |
Journal Title: | Seminars in Oncology |
Volume: | 30 |
Issue: | 4 Suppl.15 |
ISSN: | 0093-7754 |
Publisher: | Elsevier Inc. |
Date Published: | 2003-08-01 |
Start Page: | 26 |
End Page: | 33 |
Language: | English |
PUBMED: | 14523792 |
PROVIDER: | scopus |
DOI: | 10.1016/S0093-7754(03)00402-0 |
DOI/URL: | |
Notes: | Export Date: 25 September 2014 -- Source: Scopus |