Web based pathology assessment in RTOG 98-04 Journal Article


Authors: Woodward, W. A.; Sneige, N.; Winter, K.; Kuerer, H. M.; Hudis, C.; Rakovitch, E.; Smith, B. L.; Pierce, L. J.; Germano, I.; Pu, A. T.; Walker, E. M.; Grisell, D. L.; White, J. R.; McCormick, B.
Article Title: Web based pathology assessment in RTOG 98-04
Abstract: Aims: Radiation Therapy Oncology Group 98-04 sought to identify women with 'good risk' ductal carcinoma in situ (DCIS) who receive no significant benefit from radiation. Enrolment criteria excluded close or positive margins and grade 3 disease. To ensure reproducibility in identifying good risk pathology, an optional web based teaching tool was developed and a random sampling of 10% of submitted slides were reviewed by a central pathologist. Methods: Submitting pathologists were asked to use the web based teaching tool and submit an assessment of the tool along with the pathology specimen form and DCIS H&E stained slide. Per protocol pathology was centrally reviewed for 10% of the cases. Results: Of the 55 DCIS cases reviewed, three had close or positive margins and three were assessed to include grade 3 DCIS, therefore 95% of DCIS cases reviewed were correctly graded, and 89% reviewed were pathologically appropriate for enrolment. Regarding the teaching tool, 13% of DCIS cases included forms that indicated the website was used. One of these seven who used the website submitted DCIS of grade 3. Conclusions: Central review demonstrates high pathological concordance with enrolment eligibility, particularly with regard to accurate grading. The teaching tool appeared to be underused.
Keywords: cancer radiotherapy; cancer grading; internet; teaching; pathology; intraductal carcinoma; human; priority journal; article
Journal Title: Journal of Clinical Pathology
Volume: 67
Issue: 9
ISSN: 0021-9746
Publisher: BMJ Publishing Group Ltd.  
Date Published: 2014-09-01
Start Page: 777
End Page: 780
Language: English
DOI: 10.1136/jclinpath-2014-202370
PROVIDER: scopus
PMCID: PMC4145412
PUBMED: 24989024
DOI/URL:
Notes: Export Date: 1 October 2014 -- Source: Scopus
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  1. Clifford Hudis
    905 Hudis
  2. Beryl McCormick
    371 McCormick