Targeted cancer therapies Journal Article

Authors: Yan, L.; Rosen, N.; Arteaga, C.
Article Title: Targeted cancer therapies
Abstract: With unprecedented understanding of molecular events underlying human cancer in this genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers to which tumors are potentially addicted to have been developed and continue to be developed. These targeted cancer therapies are being actively tested in clinical trials with mixed successes. This editorial provides an overview on successful targeted cancer drugs on the market and those drugs that are in late clinical development stages. Importantly, the article lays out main challenges in developing molecular targeted therapies and potential path forward to overcome these challenges, as well as opportunities for China in this new era of targeted agents. The editorial serves as an introduction to the Targeted Cancer Therapies series that will review in depth of major pathways and drugs targeting these pathways to be published in the coming issues of the Chinese Journal of Cancer.
Keywords: drug efficacy; monotherapy; nonhuman; patient selection; antineoplastic agents; clinical trials as topic; drug targeting; neoplasms; animals; editorial; cancer therapy; patient identification; china; experimental model; molecularly targeted therapy; molecular targeted therapy
Journal Title: Chinese Journal of Cancer
Volume: 30
Issue: 1
ISSN: 1000-467X
Publisher: Landes Bioscience Guangzhou  
Date Published: 2011-01-01
Start Page: 1
End Page: 4
Language: English
PROVIDER: scopus
PUBMED: 21192839
PMCID: PMC4012258
DOI: 10.5732/cjc.010.10553
Notes: --- - "Export Date: 23 June 2011" - "Source: Scopus"
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MSK Authors
  1. Neal Rosen
    395 Rosen
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