T-cell immunotherapy: Looking forward Journal Article
| Authors: | Corrigan-Curay, J.; Kiem, H. P.; Baltimore, D.; O'Reilly, M.; Brentjens, R. J.; Cooper, L.; Forman, S.; Gottschalk, S.; Greenberg, P.; Junghans, R.; Heslop, H.; Jensen, M.; Mackall, C.; June, C.; Press, O.; Powell, D.; Ribas, A.; Rosenberg, S.; Sadelain, M.; Till, B.; Patterson, A. P.; Jambou, R. C.; Rosenthal, E.; Gargiulo, L.; Montgomery, M.; Kohn, D. B. |
| Article Title: | T-cell immunotherapy: Looking forward |
| Abstract: | The rapidly expanding field of T-cell immunotherapy has experienced clinical successes along with some serious toxicities. "T Cell Immunotherapy: Optimizing Trial Design," a workshop sponsored by the National Institutes of Health's (NIH's) Office of Biotechnology Activities (OBA), brought together researchers to discuss the scientific advances and share new data on key trial design issues, including the selection of new targets, optimizing the T-cell population, preconditioning regimens, strategies to promote persistence of cells, and analysis and management of acute reactions to T-cell infusions with the goal of identifying best practices and a research agenda that will facilitate further development and maximize the safety of this promising approach. © The American Society of Gene & Cell Therapy. |
| Journal Title: | Molecular Therapy |
| Volume: | 22 |
| Issue: | 9 |
| ISSN: | 1525-0016 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2014-09-01 |
| Start Page: | 1564 |
| End Page: | 1574 |
| Language: | English |
| DOI: | 10.1038/mt.2014.148 |
| PROVIDER: | scopus |
| PUBMED: | 25186558 |
| PMCID: | PMC4435492 |
| DOI/URL: | |
| Notes: | Export Date: 1 October 2014 -- Source: Scopus |
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