Human xenograft transplantation in animal research: Risk assessment and hazard control for animal care workers Journal Article


Author: Zel, P.
Article Title: Human xenograft transplantation in animal research: Risk assessment and hazard control for animal care workers
Abstract: The use of human xenograft transplants in research animals continues to be a powerful tool for studying cancer biology, imaging technologies, developing new anti-cancer therapies, and determining the pharmacological and toxicological effects of these treatments. It is important to recognize that human cells and tissues have the potential for carrying bloodborne pathogens or other potentially infectious materials. A risk assessment will determine the procedures and special equipment that are necessary to protectworkers from accidental exposure to these biohazards. Effective use of personal protective equipment and engineering controls will reduce the risk of biohazard exposure.
Keywords: review; nonhuman; animals; practice guideline; bacteria (microorganisms); cancer research; risk assessment; animalia; experimental animal; xenograft; transplantation, heterologous; health care personnel; virus infection; bacterial infection; infection control; environmental exposure; infection risk; disease transmission; occupational exposure; health hazard; parasitosis; humans; human; hazardous waste; animal care committees; animal technicians; hazardous substances
Journal Title: Contemporary Topics in Laboratory Animal Science
Volume: 42
Issue: 6
ISSN: 1060-0558
Publisher: Amer Assoc Laboratory Animal Science  
Date Published: 2003-11-01
Start Page: 64
End Page: 65
Language: English
PUBMED: 14661648
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 25 September 2014 -- Source: Scopus
Citation Impact
MSK Authors
  1. Paul M Zel
    2 Zel