Management of major hemorrhage during mediastinoscopy Journal Article


Authors: Park, B. J.; Flores, R.; Downey, R. J.; Bains, M. S.; Rusch, V. W.
Article Title: Management of major hemorrhage during mediastinoscopy
Abstract: Objective: The management of major hemorrhage complicating mediastinoscopy is not well described. We reviewed our experience to determine the frequency, optimal management strategy, and outcome of these injuries. Methods: A retrospective review of all mediastinoscopies performed at a single institution during a 12-year period (January 1990-January 2002) was performed. Major hemorrhage was defined as that requiring exploration for definitive control. Results: During the study period, 3391 mediastinoscopies were performed. Fourteen patients (0.4%) experienced major hemorrhage. Most patients (12/14) had non-small cell lung cancer, and only 1 patient each underwent preoperative radiation, repeat mediastinoscopy, or extended mediastinoscopy. The most common biopsy site (4/14 cases) resulting in major hemorrhage was the lower right paratracheal region (level 4R), and the most frequently injured vessels were the azygos vein and the innominate and pulmonary arteries. Initial control of hemorrhage was achieved through packing in 93% (13/14), and the most common initial approach for exploration was sternotomy (8/14). Four patients underwent a planned pulmonary resection after definitive control of bleeding. The median amount of blood transfused was 2 units (range 0-18 units). Postoperative complications occurred in 2 of 14 patients (14%). There were no intraoperative deaths, but 1 patient died postoperatively (1/14, 7% mortality). The median postoperative length of stay was 6 days (range 1-19 days). Conclusions: Major hemorrhage during mediastinoscopy is an uncommon but potentially morbid event. Initial control can usually be achieved through packing. Subsequent management presents a technical challenge but can result in minimal morbidity and mortality.
Keywords: adult; clinical article; aged; aged, 80 and over; middle aged; retrospective studies; review; cancer radiotherapy; cancer diagnosis; bleeding; lung non small cell cancer; lung resection; tumor biopsy; retrospective study; postoperative complication; length of stay; blood transfusion; surgical mortality; sternotomy; mediastinoscopy; blood loss, surgical; pulmonary artery; azygos vein; humans; human; male; female; priority journal; brachiocephalic trunk
Journal Title: Journal of Thoracic and Cardiovascular Surgery
Volume: 126
Issue: 3
ISSN: 0022-5223
Publisher: Mosby Elsevier  
Date Published: 2003-09-01
Start Page: 726
End Page: 731
Language: English
DOI: 10.1016/s0022-5223(03)00748-7
PUBMED: 14502145
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 25 September 2014 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Valerie W Rusch
    864 Rusch
  2. Raja Flores
    108 Flores
  3. Bernard J Park
    263 Park
  4. Robert J Downey
    254 Downey
  5. Manjit S Bains
    338 Bains