Classification schemes for protein structure and function Journal Article
| Authors: | Ouzounis, C. A.; Coulson, R. M. R.; Enright, A. J.; Kunin, V.; Pereira-Leal, J. B. |
| Article Title: | Classification schemes for protein structure and function |
| Abstract: | We examine the structural and functional classifications of the protein universe, providing an overview of the existing classification schemes, their features and inter-relationships. We argue that a unified scheme should be based on a natural classification approach and that more comparative analyses of the present schemes are required both to understand their limitations and to help delimit the number of known protein folds and their corresponding functional roles in cells. |
| Keywords: | carrier protein; review; nonhuman; protein conformation; protein function; proteins; protein analysis; animals; classification; computational biology; protein; structure activity relation; structure-activity relationship; data base; automation; amino acid sequence; algorithm; forecasting; protein folding; protein structure; tryptophan; enzyme; isomerase; synthetase; nucleic acid binding protein; humans; priority journal; indole 3 glycerol phosphate synthase; structural protein |
| Journal Title: | Nature Reviews Genetics |
| Volume: | 4 |
| Issue: | 7 |
| ISSN: | 1471-0056 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2003-07-01 |
| Start Page: | 508 |
| End Page: | 519 |
| Language: | English |
| DOI: | 10.1038/nrg1113 |
| PUBMED: | 12838343 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 25 September 2014 -- Source: Scopus |
