Authors: | Oosterwijk, E.; Divgi, C. R.; Brouwers, A.; Boerman, O. C.; Larson, S. M.; Mulders, P.; Old, L. J. |
Article Title: | Monoclonal antibody-based therapy for renal cell carcinoma |
Abstract: | Monoclonal antibody G250 treatment may have a role in the management of metastatic RCC; however, particular subgroups who are more prone to benefit from this treatment must be delineated. High-risk patients may benefit from adjuvant treatment with this nontoxic treatment modality. Large cohort studies are needed to investigate this possibility. |
Keywords: | unclassified drug; review; risk benefit analysis; cell proliferation; cohort analysis; drug effect; cancer therapy; kidney carcinoma; kidney neoplasms; high risk patient; monoclonal antibody; antibodies, monoclonal; antigens, neoplasm; monoclonal antibody g250; drug accumulation; carcinoma, renal cell; antigen specificity; immunogenicity; antibody specificity; target cell; multidrug resistance; cell killing; antibody dependent cellular cytotoxicity; humans; human; priority journal; drug cross reactivity |
Journal Title: | Urologic Clinics of North America |
Volume: | 30 |
Issue: | 3 |
ISSN: | 0094-0143 |
Publisher: | W.B. Saunders Co-Elsevier Inc. |
Date Published: | 2003-08-01 |
Start Page: | 623 |
End Page: | 631 |
Language: | English |
DOI: | 10.1016/s0094-0143(03)00028-4 |
PUBMED: | 12953760 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Export Date: 25 September 2014 -- Source: Scopus |