Monoclonal antibody-based therapy for renal cell carcinoma Journal Article


Authors: Oosterwijk, E.; Divgi, C. R.; Brouwers, A.; Boerman, O. C.; Larson, S. M.; Mulders, P.; Old, L. J.
Article Title: Monoclonal antibody-based therapy for renal cell carcinoma
Abstract: Monoclonal antibody G250 treatment may have a role in the management of metastatic RCC; however, particular subgroups who are more prone to benefit from this treatment must be delineated. High-risk patients may benefit from adjuvant treatment with this nontoxic treatment modality. Large cohort studies are needed to investigate this possibility.
Keywords: unclassified drug; review; risk benefit analysis; cell proliferation; cohort analysis; drug effect; cancer therapy; kidney carcinoma; kidney neoplasms; high risk patient; monoclonal antibody; antibodies, monoclonal; antigens, neoplasm; monoclonal antibody g250; drug accumulation; carcinoma, renal cell; antigen specificity; immunogenicity; antibody specificity; target cell; multidrug resistance; cell killing; antibody dependent cellular cytotoxicity; humans; human; priority journal; drug cross reactivity
Journal Title: Urologic Clinics of North America
Volume: 30
Issue: 3
ISSN: 0094-0143
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2003-08-01
Start Page: 623
End Page: 631
Language: English
DOI: 10.1016/s0094-0143(03)00028-4
PUBMED: 12953760
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 25 September 2014 -- Source: Scopus
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  1. Chaitanya Divgi
    163 Divgi
  2. Steven M Larson
    959 Larson
  3. Lloyd J Old
    593 Old