Instruments and new technologies for the in vivo diagnosis of melanoma Journal Article


Authors: Marghoob, A. A.; Swindle, L. D.; Moricz, C. Z. M.; Sanchez Negron, F. A.; Slue, B.; Halpern, A. C.; Kopf, A. W.
Article Title: Instruments and new technologies for the in vivo diagnosis of melanoma
Abstract: The principal objective of screening individuals at risk for melanoma is detection of cutaneous melanoma during the curable stages of its early evolution. Unaided visual inspection of the skin is often suboptimal at diagnosing melanoma. Improving the diagnostic accuracy for melanoma remains an area of active research. These research efforts have focused on both the detection of early melanoma and the in-depth evaluation of suspicious pigmented lesions for the presence of absence of melanoma. Numerous instruments are under investigation to determine their usefulness in imaging and ascertaining a correct in vivo diagnosis of melanoma. It is anticipated that some of these tools, alone or in combination, will improve our ability to differentiate, in vivo, melanoma from its simulators. Ultimately, these advances may prevent unnecessary biopsies (increased specificity) while increasing the sensitivity for diagnosing melanoma. This article reviews the current instruments and new technologies for the in vivo diagnosis of melanoma.
Keywords: review; cancer staging; magnetic resonance imaging; diagnostic accuracy; sensitivity and specificity; diagnostic procedure; melanoma; microscopy, confocal; skin neoplasms; cancer screening; tumor biopsy; in vivo study; medical instrumentation; device; high risk population; equipment design; photography; dermatology; technology; diagnosis, computer-assisted; light; tomography, optical coherence; humans; priority journal
Journal Title: Journal of the American Academy of Dermatology
Volume: 49
Issue: 5
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2003-11-01
Start Page: 777
End Page: 797
Language: English
DOI: 10.1016/s0190-9622(03)02470-8
PUBMED: 14576657
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 25 September 2014 -- Source: Scopus
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MSK Authors
  1. Allan C Halpern
    396 Halpern
  2. Ashfaq A Marghoob
    534 Marghoob
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