Symptom control in patients with locally recurrent rectal cancer Journal Article
| Authors: | Miner, T. J.; Jaques, D. P.; Paty, P. B.; Guillem, J. G.; Wong, W. D. |
| Article Title: | Symptom control in patients with locally recurrent rectal cancer |
| Abstract: | BACKGROUND: Although resection of locally recurrent rectal cancer has been associated with improved survival, clinical outcomes after such repeat surgery have been incompletely characterized. METHODS: From 1997 to 1999, 105 consecutive patients requiring repeat surgery for locally recurrent rectal cancer were identified. Patients were observed for a minimum of 2 years or until death. RESULTS: An operation was performed with palliative intent in 23% of patients. Before repeat surgery, 79% of the palliative-intent patients had symptoms: 21% bleeding, 42% obstruction, and 21% pain. After repeat surgery with palliative intent, improvement was noted in 40% with bleeding, 70% with obstruction, and 20% with pain. Additional or recurrent symptoms were noted in 87% during follow-up. Seventy-seven percent of patients had an operation with nonpalliative intent. Before repeat surgery, 57% of nonpalliative patients had symptoms, with 32% experiencing bleeding, 11% obstruction, and 19% pain. After repeat surgery with nonpalliative intent, initial improvement was noted in 88% with bleeding, 78% with obstruction, and 40% with pain. During follow-up, symptoms arose in 37% of the initially asymptomatic patients, and additional or recurrent symptoms were seen in 63% of those previously symptomatic. CONCLUSIONS: Although symptomatic relief is associated with repeat surgery, the recurrence or development of alternate symptoms makes a completely asymptomatic clinical course uncommon. |
| Keywords: | adult; aged; aged, 80 and over; disease-free survival; middle aged; mortality; gastrointestinal hemorrhage; disease free survival; follow up; follow-up studies; palliative care; pain; neoplasm recurrence, local; palliative therapy; tumor recurrence; reoperation; intestine obstruction; intestinal obstruction; rectal neoplasms; rectum tumor; humans; human; male; female; article |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 10 |
| Issue: | 1 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 2003-01-01 |
| Start Page: | 72 |
| End Page: | 79 |
| Language: | English |
| PUBMED: | 12513964 |
| PROVIDER: | scopus |
| DOI: | 10.1245/ASO.2003.03.040 |
| DOI/URL: | |
| Notes: | Export Date: 12 September 2014 -- Source: Scopus |
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