Neuropathic pain in patients with cancer Journal Article
| Authors: | Manfredi, P. L.; Gonzales, G. R.; Sady, R.; Chandler, S.; Payne, R. |
| Article Title: | Neuropathic pain in patients with cancer |
| Abstract: | We provide a detailed description of painful neural lesions in hospitalized patients with cancer. A total of 187 consecutive patients with cancer and pain, referred to the pain service of a cancer hospital, were evaluated within 24 hours by two neurologists and followed until discharge or death. Based on history, pain descriptors, physical examination, and radiological and electrophysiological studies, the pain was categorized as neuropathic in 103 patients. The most frequent sites of neurological injury were nerve roots, spinal cord and cauda equina, brachial and lumbosacral plexus, and peripheral nerves. There were no patients with pain caused by injury to the brain. In 93 of these patients, the pain was caused by ongoing neural injury, while, in 10 patients, the neural injury was old and stable. Within these two groups of patients with neuropathic pain, analgesic treatments differed. Prospective studies may determine if categorizing painful neurological injuries in cancer patients based on inferred pathophysiology is useful when deciding among different treatment options. |
| Keywords: | adolescent; adult; child; controlled study; aged; aged, 80 and over; middle aged; major clinical study; cancer patient; antineoplastic agent; neoplasms; cancer palliative therapy; pain; opiate; steroid; cancer pain; cancer center; death; nonsteroid antiinflammatory agent; antidepressant agent; nerve injury; hospital patient; hospital discharge; physical examination; pain measurement; anticonvulsive agent; analgesia; pain assessment; neuropathic pain; radiodiagnosis; electrophysiology; spinal cord injury; peripheral nervous system diseases; analgesic agent; lumbosacral plexus; cauda equina; peripheral nerve injury; brachial plexus; humans; human; male; female; article; nerve root injury |
| Journal Title: | Journal of Palliative Care |
| Volume: | 19 |
| Issue: | 2 |
| ISSN: | 0825-8597 |
| Publisher: | Centre Recherche Institut Univ Geriatrie Montreal |
| Date Published: | 2003-01-01 |
| Start Page: | 115 |
| End Page: | 118 |
| Language: | English |
| PUBMED: | 12955928 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 12 September 2014 -- Source: Scopus |
