Authors: | Kennedy, J. G.; Donahue, J. R.; Aydin, H.; Hoang, B. H.; Huvos, A.; Morris, C. |
Article Title: | Metastatic breast carcinoma to bone disguised by osteopoikilosis |
Abstract: | A case of metastatic lobular carcinoma of the breast in conjunction with osteopoikilosis is described. Widespread diffuse sclerotic bone lesions were identified on radiographs in a patient with breast carcinoma. In addition computed tomography demonstrated discrete spherical areas of increased density throughout the skeleton manifest typically by osteopoikilosis. No systemic symptoms were evident, blood parameters were normal and the lesions did not demonstrate any increased uptake of technetium on bone scan. An iliac crest bone biopsy, however, revealed metastatic disease in addition to osteopoikilosis. Conventional radiological investigations may not delineate metastasis on a background of bone dysplasia. |
Keywords: | adult; bone neoplasms; middle aged; case report; bone metastasis; computer assisted tomography; image analysis; diagnosis, differential; breast neoplasms; symptom; bone lesion; blood analysis; breast carcinoma; radiography; density; metastatic breast cancer; bone scintiscanning; bone radiography; carcinoma, lobular; osteosclerosis; bone biopsy; pelvic bones; technetium; iliac crest; humans; human; female; priority journal; article; medronic acid; osteopoikilosis |
Journal Title: | Skeletal Radiology |
Volume: | 32 |
Issue: | 4 |
ISSN: | 0364-2348 |
Publisher: | Springer |
Date Published: | 2003-04-01 |
Start Page: | 240 |
End Page: | 243 |
Language: | English |
PUBMED: | 12652341 |
PROVIDER: | scopus |
DOI: | 10.1007/s00256-002-0605-x |
DOI/URL: | |
Notes: | Export Date: 12 September 2014 -- Source: Scopus |