Metastatic breast carcinoma to bone disguised by osteopoikilosis Journal Article


Authors: Kennedy, J. G.; Donahue, J. R.; Aydin, H.; Hoang, B. H.; Huvos, A.; Morris, C.
Article Title: Metastatic breast carcinoma to bone disguised by osteopoikilosis
Abstract: A case of metastatic lobular carcinoma of the breast in conjunction with osteopoikilosis is described. Widespread diffuse sclerotic bone lesions were identified on radiographs in a patient with breast carcinoma. In addition computed tomography demonstrated discrete spherical areas of increased density throughout the skeleton manifest typically by osteopoikilosis. No systemic symptoms were evident, blood parameters were normal and the lesions did not demonstrate any increased uptake of technetium on bone scan. An iliac crest bone biopsy, however, revealed metastatic disease in addition to osteopoikilosis. Conventional radiological investigations may not delineate metastasis on a background of bone dysplasia.
Keywords: adult; bone neoplasms; middle aged; case report; bone metastasis; computer assisted tomography; image analysis; diagnosis, differential; breast neoplasms; symptom; bone lesion; blood analysis; breast carcinoma; radiography; density; metastatic breast cancer; bone scintiscanning; bone radiography; carcinoma, lobular; osteosclerosis; bone biopsy; pelvic bones; technetium; iliac crest; humans; human; female; priority journal; article; medronic acid; osteopoikilosis
Journal Title: Skeletal Radiology
Volume: 32
Issue: 4
ISSN: 0364-2348
Publisher: Springer  
Date Published: 2003-04-01
Start Page: 240
End Page: 243
Language: English
PUBMED: 12652341
PROVIDER: scopus
DOI: 10.1007/s00256-002-0605-x
DOI/URL:
Notes: Export Date: 12 September 2014 -- Source: Scopus
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MSK Authors
  1. Hakan Aydin
    2 Aydin
  2. Bang Hoang
    17 Hoang
  3. Carol Morris
    53 Morris
  4. Andrew G Huvos
    196 Huvos