A concise route to the core pentasaccharide of N-linked glycoproteins Journal Article
| Authors: | Dudkin, V. Y.; Miller, J. S.; Danishefsky, S. J. |
| Article Title: | A concise route to the core pentasaccharide of N-linked glycoproteins |
| Abstract: | A concise preparation of the common pentasaccharide core of the N-linked glycoproteins is described. The reducing end glycal is functionalized at the level of chitobiose, which is then β-mannosylated using Crich's direct coupling protocol. Deprotection of the branching mannose residue, and di-α-mannosylation complete the synthesis. © 2003 Elsevier Science Ltd. All rights reserved. |
| Keywords: | glycoprotein; chemical reaction; synthesis; stereochemistry; proton nuclear magnetic resonance; chemical bond; pentasaccharide; deprotection reaction; mannose; article; mannosylation |
| Journal Title: | Tetrahedron Letters |
| Volume: | 44 |
| Issue: | 9 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 2003-02-24 |
| Start Page: | 1791 |
| End Page: | 1793 |
| Language: | English |
| DOI: | 10.1016/s0040-4039(03)00101-1 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 12 September 2014 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
-
6Miller -
10
Dudkin -
539Danishefsky
Related MSK Work