Erythromelalgia precipitated by acral erythema in the setting of thrombocytopenia Journal Article


Authors: Coppa, L. M.; Nehal, K. S.; Young, J. W.; Halpern, A. C.
Article Title: Erythromelalgia precipitated by acral erythema in the setting of thrombocytopenia
Abstract: Erythromelalgia is a rare syndrome that is characterized by episodic attacks of burning pain in the distal extremities, which last from minutes to days and are precipitated by exercise, warmth, or limb dependency. There is a primary or idiopathic form and a secondary form that occur with myeloproliferative or other diseases. All previous reports about erythromelalgia that is the result of a myeloproliferative process have documented associated thrombocytosis. We describe a 40-year-old woman with myelodysplastic syndrome who experienced erythromelalgia in the setting of acral erythema and thrombocytopenia, first induced by chemotherapy and recurring after a radiation- and chemotherapy-based myeloablative regimen that was administered before a T-cell-depleted allogeneic bone marrow transplantation.
Keywords: adult; cancer chemotherapy; prednisone; clinical feature; case report; cancer radiotherapy; cytarabine; follow up; antineoplastic agent; etoposide; thrombocytopenia; antineoplastic combined chemotherapy protocols; cyclophosphamide; steroid; allogenic bone marrow transplantation; thiotepa; symptom; myelodysplastic syndrome; acetylsalicylic acid; mitoxantrone; erythema; methylprednisolone; idarubicin; bone marrow transplantation; burning sensation; myelodysplastic syndromes; humans; human; female; priority journal; article; headache and facial pain; chiari frommel syndrome; erythromelalgia
Journal Title: Journal of the American Academy of Dermatology
Volume: 48
Issue: 6
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2003-06-01
Start Page: 973
End Page: 975
Language: English
DOI: 10.1067/mjd.2003.304
PUBMED: 12789198
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 12 September 2014 -- Source: Scopus
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  1. Allan C Halpern
    396 Halpern
  2. Kishwer S Nehal
    278 Nehal
  3. James W Young
    318 Young