Sphenoid masses in children: Radiologic differential diagnosis with pathologic correlation Journal Article


Authors: Lui, Y. W.; Dasari, S. B.; Young, R. J.
Article Title: Sphenoid masses in children: Radiologic differential diagnosis with pathologic correlation
Abstract: Summary: Childhood central skull base masses are rare, often difficult to diagnose, and have overlapping imaging findings. In this review, we provide an overview of the epidemiology, clinical findings, and management of pediatric sphenoid bone and sphenoid sinus masses with an emphasis on imaging findings that may help to differentiate lesions. Radiologic-pathologic correlation is provided. Finally, an imaging-based algorithm is presented as a guide to help radiologists narrow their differential diagnoses. Some of the entities discussed are virtually unique to the pediatric population; others occur rarely in this age group but should be considered in the appropriate clinical setting. Entities included in the discussion are grouped into 2 categories: those that cause nonaggressive osseous remodeling and those that are more commonly associated with aggressive bone changes. Mucocele, aneurysmal bone cyst, giant cell lesions, meningioma, and fibrous dysplasia tend to remodel bone, while entities such as chordoma, craniopharyngioma, rhabdomyosarcoma, sinonasal carcinoma, and neuroblastoma may cause more aggressive local bone changes. Copyright © 2011 by the American Society of Neuroradiology.
Keywords: cancer chemotherapy; cancer survival; cancer surgery; excision; review; artificial embolism; cancer patient; cancer radiotherapy; nuclear magnetic resonance imaging; follow up; cancer diagnosis; neurofibromatosis; disease association; computer assisted tomography; differential diagnosis; childhood cancer; survival time; neuroblastoma; conservative treatment; cystic fibrosis; radiosurgery; craniopharyngioma; meningioma; rhabdomyosarcoma; genetic predisposition; bone remodeling; chordoma; skull cancer; angiography; bone scintiscanning; mucocele; giant cell tumor; pilocytic astrocytoma; albright syndrome; aneurysmal bone cyst; fibrous dysplasia; giant cell granuloma; nasopharynx fibroma; paranasal sinus carcinoma; skull radiography; sphenoid; sphenoid sinus
Journal Title: American Journal of Neuroradiology
Volume: 32
Issue: 4
ISSN: 0195-6108
Publisher: American Society of Neuroradiology  
Date Published: 2011-04-01
Start Page: 617
End Page: 626
Language: English
DOI: 10.3174/ajnr.A2144
PROVIDER: scopus
PUBMED: 20595365
PMCID: PMC7965862
DOI/URL:
Notes: --- - "Export Date: 23 June 2011" - "CODEN: AAJND" - "Source: Scopus"
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  1. Robert J Young
    228 Young
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