Clinical approach to diagnosis and management of endometrial hyperplasia and carcinoma Journal Article


Authors: Leitao, M. M.; Barakat, R. R.
Article Title: Clinical approach to diagnosis and management of endometrial hyperplasia and carcinoma
Abstract: This article focuses on the most important neoplastic epithelial lesions of the uterus, endometrial hyperplasia and carcinoma. The primary management of hyperplastic lesions and carcinoma is often surgical but nonsurgical options are possible for both, depending on specific patients and tumor characteristics. Many controversies still exist regarding the optimal medical and surgical treatments of hyperplasias and carcinomas of the endometrium. There is a need to more accurately select patients for lymph node sampling or dissection. The role of adjuvant therapies for endometrial carcinomas is still under investigation. This review covers current understanding in the diagnosis and clinical management of endometrial hyperplasias and carcinomas. © 2011 Elsevier Inc.
Keywords: cancer survival; clinical feature; histopathology; review; cancer adjuvant therapy; lymph node metastasis; endometrium carcinoma; lymph node dissection; sentinel lymph node; medical decision making; clinical assessment; differential diagnosis; hyperplasia; endometrial carcinoma; uterus; endometrium; megestrol acetate; medroxyprogesterone acetate; gestagen; progesterone; complex atypical hyperplasia; endometrium hyperplasia; cancer treatment
Journal Title: Surgical Pathology Clinics
Volume: 4
Issue: 1
ISSN: 1875-9181
Publisher: Elsevier Inc.  
Date Published: 2011-03-01
Start Page: 113
End Page: 130
Language: English
DOI: 10.1016/j.path.2010.03.002
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 23 June 2011" - "Source: Scopus"
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  1. Richard R Barakat
    629 Barakat
  2. Mario Leitao
    575 Leitao