Predicting sensitivity of non-small-cell lung cancer to gefitinib: Is there a role for P-Akt Journal Article
| Authors: | Pao, W.; Miller, V. A.; Venkatraman, E.; Kris, M. G. |
| Article Title: | Predicting sensitivity of non-small-cell lung cancer to gefitinib: Is there a role for P-Akt |
| Keywords: | immunohistochemistry; signal transduction; mitogen activated protein kinase; protein kinase b; cancer survival; protein phosphorylation; treatment outcome; oncoprotein; gene mutation; proto-oncogene proteins; clinical trial; cigarette smoking; raf protein; antineoplastic agents; drug approval; note; drug targeting; antineoplastic agent; protein function; cell proliferation; metabolism; cell survival; gene targeting; enzyme inhibition; lung non small cell cancer; carcinoma, non-small-cell lung; lung neoplasms; epidermal growth factor receptor; editorial; receptor, epidermal growth factor; in vitro study; drug effect; enzyme inhibitor; protein serine threonine kinase; protein tyrosine kinase; drug selectivity; phosphatidylinositol 3 kinase; prediction; drug receptor binding; lung tumor; gene expression regulation; gene activation; gene expression regulation, neoplastic; drug antagonism; drug mechanism; enzyme inhibitors; protein-serine-threonine kinases; drug response; proto-oncogene proteins c-akt; gefitinib; tyrosine kinase receptor; prediction and forecasting; predictive value of tests; binding site; lung alveolus cell carcinoma; ras protein; thorax radiography; sex difference; protein-tyrosine kinases; adenosine triphosphate; quinazolines; drug sensitivity; mitogen activated protein kinase kinase; mitogen-activated protein kinase kinases; quinazoline derivative; downstream processing; akt1 protein, human; humans; prognosis; human; priority journal |
| Journal Title: | JNCI: Journal of the National Cancer Institute |
| Volume: | 96 |
| Issue: | 15 |
| ISSN: | 0027-8874 |
| Publisher: | Oxford University Press |
| Date Published: | 2004-08-04 |
| Start Page: | 1117 |
| End Page: | 1119 |
| Language: | English |
| PUBMED: | 15292378 |
| PROVIDER: | scopus |
| DOI: | 10.1093/jnci/djh244 |
| DOI/URL: | |
| Notes: | Cited By (since 1996):28 -- Export Date: 16 June 2014 -- CODEN: JNCIA -- Source: Scopus |
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