Early gallbladder carcinoma: A clinicopathologic study of 13 cases of intramucosal carcinoma Journal Article
| Authors: | Albores-Saavedra, J.; Chable-Montero, F.; Angeles-Albores, D.; Schwartz, A.; Klimstra, D. S.; Henson, D. E. |
| Article Title: | Early gallbladder carcinoma: A clinicopathologic study of 13 cases of intramucosal carcinoma |
| Abstract: | We report the clinicopathologic features of 13 cases of intramucosal carcinoma (IMC) of the gallbladder. All IMCs were incidental findings in cholecystectomy specimens for cholelithiasis. However, one of the patients had a carcinoma of the pancreas, and the gallbladder incidentally removed during the Whipple procedure showed an IMC. Another patient had a small cell carcinoma of the gallbladder, and one of the sections showed an IMC. Of the IMCs, 10 were well-differentiated adenocarcinomas, 1 was a moderately differentiated adenocarcinoma, 1 was an undifferentiated carcinoma, and 1 was a squamous cell carcinoma. Of the patients, 8 were disease-free from 3 to 11 years, and 2 patients died, one as a result of the pancreatic ductal carcinoma and the other with disseminated metastases of the small cell carcinoma. The follow-up of another patient was too short to be significant. Two patients were lost to follow-up. Our findings suggest that a simple cholecystectomy is a curative procedure for IMCs of the gallbladder. © American Society for Clinical Pathology. |
| Keywords: | adult; cancer chemotherapy; clinical article; aged; middle aged; survival rate; carcinoma, squamous cell; disease free survival; antineoplastic agent; adenocarcinoma; cancer mortality; pancreas carcinoma; early cancer; incidental findings; carcinoma in situ; neoplasm invasiveness; cholecystectomy; gallbladder carcinoma; gallbladder neoplasms; cholelithiasis; mucous membrane; carcinoma, small cell; precancerous conditions; clinical course; gallbladder; histologic types; intramucosal carcinoma |
| Journal Title: | American Journal of Clinical Pathology |
| Volume: | 135 |
| Issue: | 4 |
| ISSN: | 0002-9173 |
| Publisher: | Oxford University Press |
| Date Published: | 2011-04-01 |
| Start Page: | 637 |
| End Page: | 642 |
| Language: | English |
| DOI: | 10.1309/ajcpfrkcfedlv03y |
| PUBMED: | 21411787 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 23 June 2011" - "CODEN: AJCPA" - "Source: Scopus" |
