Treatments for noncutaneous melanoma Journal Article


Authors: Khalil, D. N.; Carvajal, R. D.
Article Title: Treatments for noncutaneous melanoma
Abstract: Historically the approach to treating noncutaneous melanoma was largely guided by the experience with cutaneous melanoma, particularly in the metastatic setting. However, as genetic tools have allowed clinicians to better characterize these malignancies, their unique biology has become apparent. The ability to accurately distinguish the subtypes of melanoma and the genetic alterations that drive them is beginning to yield the tools that are shifting this disease from one that has proved to be intractable in the advanced setting to one that can be effectively treated. © 2014 Elsevier Inc.
Keywords: cancer surgery; gene mutation; overall survival; review; cisplatin; interferon; chemoembolization; drug efficacy; cancer adjuvant therapy; cancer radiotherapy; comparative study; temozolomide; cancer staging; lymph node dissection; imatinib; dacarbazine; ipilimumab; melanoma; melphalan; liver metastasis; iodine 125; brachytherapy; enucleation; external beam radiotherapy; uvea melanoma; photodynamic therapy; cobalt 60; iridium 192; palladium 103; infusion; hepatic artery; cutaneous melanoma; laser coagulation; photofrin; anorectal disease; fotemustine; metastatic melanoma; mucosal melanoma; ocular melanoma; uveal melanoma; metastasis resection; selumetinib; dabrafenib; trametinib; anorectal melanoma; vulvovaginal melanoma; transpupillary thermotherapy; eye melanoma; human; priority journal; hematoporphyrin; rhodium complex; ruthenium complex; noncutaneous melanoma; vulvovaginal disease
Journal Title: Hematology/Oncology Clinics of North America
Volume: 28
Issue: 3
ISSN: 0889-8588
Publisher: Elsevier Inc.  
Date Published: 2014-06-01
Start Page: 507
End Page: 521
Language: English
DOI: 10.1016/j.hoc.2014.02.006
PROVIDER: scopus
PUBMED: 24880944
DOI/URL:
Notes: Hematol. Oncol. Clin. North Am. -- Export Date: 8 July 2014 -- CODEN: HCNAE -- Source: Scopus
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  1. Richard D Carvajal
    148 Carvajal
  2. Danny Nejad Khalil
    64 Khalil