Margins in breast conservation: A clinician's perspective and what the literature tells us Journal Article
| Authors: | Houssami, N.; Morrow, M. |
| Article Title: | Margins in breast conservation: A clinician's perspective and what the literature tells us |
| Abstract: | The optimal margin in breast-conserving surgery is controversial, and re-excision is common. Pathologic margin assessment is not standardized, and tumor biology and the use of systemic therapy have a major impact on local control. A study-level meta-Analysis found no difference in local recurrence for margin widths of 1, 2, and 5 mm, leading a multidisciplinary panel to recommend adoption of no ink on tumor as the standard definition of a negative margin. © 2014 Wiley Periodicals, Inc. |
| Keywords: | cancer chemotherapy; primary tumor; surgical technique; review; cancer recurrence; systemic therapy; cancer radiotherapy; methotrexate; cancer staging; breast cancer; tumor volume; cyclophosphamide; practice guideline; distant metastasis; cancer hormone therapy; minimal residual disease; breast carcinoma; partial mastectomy; medical society; tamoxifen; surgery; cancer control; anthracycline; intraductal carcinoma; margins; re-excision; surgical margin; local recurrence; triple negative breast cancer; breast-conserving surgery; tumor invasion; human; priority journal |
| Journal Title: | Journal of Surgical Oncology |
| Volume: | 110 |
| Issue: | 1 |
| ISSN: | 0022-4790 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2014-07-01 |
| Start Page: | 2 |
| End Page: | 7 |
| Language: | English |
| DOI: | 10.1002/jso.23594 |
| PROVIDER: | scopus |
| PUBMED: | 24756965 |
| DOI/URL: | |
| Notes: | J. Surg. Oncol. -- Export Date: 8 July 2014 -- CODEN: JSONA -- Source: Scopus |
