Drug nephropathies Book Section
| Author: | Glezerman, I. G. |
| Editors: | Finkel, K. W.; Howard, S. C. |
| Article/Chapter Title: | Drug nephropathies |
| Abstract: | Over the past several decades significant strides have been made in the development of cancer chemotherapy. Unfortunately, a variety of unanticipated side-effects have been discovered with a number of drugs affecting renal function. Both glomerular and tubular damage have been reported with chemotherapy, and more recently hypertension, proteinuria and electrolyte abnormalities were noted with the introduction of newer biological anti-cancer agents. In this chapter, the incidence of nephrotoxicity, purported mechanisms, clinical presentation and preventive strategies will be reviewed for drugs with potential for renal toxicity. © 2014 Elsevier Inc. All rights reserved. |
| Keywords: | hypertension; hypophosphatemia; chemotherapy; nephrotoxicity; hypomagnesemia; proteinuria; thrombotic microangiopathy; side-effects; electrolyte abnormalities; tubulo-interstitial damage |
| Book Title: | Renal Disease in Cancer Patients |
| ISBN: | 978-0-12-415948-8 |
| Publisher: | Elsevier Inc. |
| Publication Place: | Amsterdam, Netherlands |
| Date Published: | 2014-01-01 |
| Start Page: | 195 |
| End Page: | 208 |
| Language: | English |
| DOI: | 10.1016/b978-0-12-415948-8.00013-1 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 13 -- Renal Dis. in Cancer Patients -- 9780124159488 (ISBN) -- Export Date: 8 July 2014 -- Source: Scopus |
