A structural view of the COPII vesicle coat Journal Article

  


Authors: Bickford, L. C.; Mossessova, E.; Goldberg, J.
Article Title: A structural view of the COPII vesicle coat
Abstract: The COPII vesicle coat coordinates the budding of transport vesicles from the endoplasmic reticulum in the initial step of the secretory pathway. The coat orchestrates a sequence of events including self-assembly on the membrane, cargo and SNARE molecule selection, and deformation of the membrane into a bud to drive vesicle fission. Recent molecular-level studies have helped to explain how the three components of yeast COPII - Sar1 GTPase, the Sec23/24 subcomplex and the Sec13/31 subcomplex - combine to organize this complex process.
Keywords: review; nonhuman; electron microscopy; complex formation; protein assembly; membrane proteins; endoplasmic reticulum; saccharomyces cerevisiae; carrier proteins; membrane protein; protein transport; phosphoproteins; models, molecular; budding; yeast; saccharomyces cerevisiae proteins; molecular biology; structure analysis; guanosine triphosphate; er; nuclear pore complex proteins; membrane vesicle; vesicular transport proteins; guanine nucleotide exchange factor; monomeric gtp-binding proteins; coated vesicle; cop-coated vesicles; snare protein; em; transport vesicle; golgi apparatus; arf; gtpase-activating protein; gef; snare; priority journal; adp ribosylation factor; coat protein complex; cop; gap; soluble n-ethylmaleimide-sensitive factor attachment protein receptor
Journal Title: Current Opinion in Structural Biology
Volume: 14
Issue: 2
ISSN: 0959-440X
Publisher: Elsevier Inc.  
Date Published: 2004-04-01
Start Page: 147
End Page: 153
Language: English
DOI: 10.1016/j.sbi.2004.02.002
PROVIDER: scopus
PUBMED: 15093828
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-1842828864&partnerID=40&md5=466b77a702a4d57ea03e74f966efe25e
Notes: Curr. Opin. Struct. Biol. -- Cited By (since 1996):38 -- Export Date: 16 June 2014 -- CODEN: COSBE -- Source: Scopus
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MSK Authors
  1. Jonathan D Goldberg
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  2. Elena Goldberg
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