Authors: | Maghami, E.; Kraus, D. H. |
Article Title: | Cancer of the nasal cavity and paranasal sinuses |
Abstract: | Sinonasal malignancies continue to have poor survival rates. Disease-related mortality is usually the result of disease recurrence and progression at the primary site despite aggressive therapy. Complete surgical excision with postoperative radiation therapy remains the standard of care for resectable lesions. Improved reconstructive techniques have increased our ability to aggressively clear locally advanced disease in this anatomically challenging region, while reducing associated functional and cosmetic morbidity. Intensive multimodality treatment regimens coupled with newer medical technology may ultimately improve the long-prevailing poor prognosis of these tumors. © Future Drugs Ltd. All rights reserved. |
Keywords: | cancer chemotherapy; cancer survival; cancer surgery; excision; surgical technique; survival rate; clinical trial; review; cancer recurrence; plastic surgery; squamous cell carcinoma; cisplatin; fluorouracil; advanced cancer; cancer growth; diarrhea; multimodality cancer therapy; treatment planning; cancer radiotherapy; postoperative care; combined modality therapy; chemotherapy; cancer staging; neurotoxicity; nuclear magnetic resonance imaging; positron emission tomography; cancer diagnosis; undifferentiated carcinoma; cancer palliative therapy; adenocarcinoma; disease association; melanoma; computer assisted tomography; bone marrow suppression; melanin; radiation; mucosa inflammation; nausea; vomiting; morbidity; kidney failure; pathology; radiation injury; cancer mortality; neuroendocrine tumor; sarcoma; postoperative complication; standard; drug fatality; grand mal seizure; medical technology; lymphoma; fluorodeoxyglucose f 18; bleomycin; outcome; surgery; sepsis; complications; electroporation; protein s 100; melan a; esthetics; adenoid cystic carcinoma; aspiration biopsy; mitomycin; alopecia; chromogranin; head and neck; paranasal sinus cancer; paranasal sinus neoplasms; esthesioneuroblastoma; paranasal sinus; nose neoplasms; cerebrovascular accident; ototoxicity; neuron specific enolase; synaptophysin; nasal cavity; functional disease; orbit metastasis; neck metastasis; gastritis; neurofilament protein; nose cavity cancer; monoclonal antibody hmb 45; cancer; humans; prognosis; human; nose mucosa |
Journal Title: | Expert Review of Anticancer Therapy |
Volume: | 4 |
Issue: | 3 |
ISSN: | 1473-7140 |
Publisher: | Taylor & Francis Group |
Date Published: | 2004-06-01 |
Start Page: | 411 |
End Page: | 424 |
Language: | English |
PROVIDER: | scopus |
PUBMED: | 15161440 |
DOI: | 10.1586/14737140.4.3.411 |
DOI/URL: | |
Notes: | Expert Rev. Anticancer Ther. -- Cited By (since 1996):8 -- Export Date: 16 June 2014 -- CODEN: ERATB C2 - 15161440 -- Source: Scopus |