Surgical management of advanced head and neck cancer Journal Article


Authors: Bentz, B. G.; Kraus, D. H.
Article Title: Surgical management of advanced head and neck cancer
Abstract: The introduction of chemotherapy to the treatment armamentarium for head and neck cancer (H&NCa) has brought about revolutionary changes in the way that we approach advanced head and neck neoplastic disease. Yet, a lack of prospective randomized data to definitively prove survival or functional benefit with the use of these new treatment paradigms underscores the fact that surgical therapy with appropriate reconstruction continues to play a central role in the treatment of advanced stage H&NCa. Because of this rapid evolution of therapeutic strategies, an individual treatment's role and its interrelationship with other modalities must be constantly reevaluated in order to tailor the most optimal treatment approach to a given clinical problem. The purpose of this review article is to discuss the present state of art for surgical extirpation and reconstruction for advanced neoplastic diseases of the head and neck. These treatment options must continue to be considered mainstay therapy for these patients until the controversies of optimal treatment strategies are adequately resolved.
Keywords: cancer surgery; review; laryngectomy; larynx carcinoma; neck dissection; advanced cancer; cancer risk; chemotherapy; lymph node metastasis; treatment indication; risk factor; symptom; head and neck cancer; physical examination; high risk population; free tissue graft; soft tissue defect; mouth carcinoma; salivary gland carcinoma; hypopharynx carcinoma; paranasal sinus carcinoma; pharynx carcinoma; human; head and neck neoplasms, diagnosis; head and neck neoplasms, surgery
Journal Title: Otorinolaringologia
Volume: 54
Issue: 2
ISSN: 0026-4938
Publisher: Edizioni Minerva Medica  
Date Published: 2004-06-01
Start Page: 81
End Page: 92
Language: English
PROVIDER: scopus
DOI/URL:
Notes: Otorinolaringologia -- Export Date: 16 June 2014 -- CODEN: OTORD -- Source: Scopus