Systemic or regional chemotherapy for liver metastases from colorectal cancer: Has the wheel stopped spinning? Journal Article
| Authors: | Zalcberg, J. R.; Kemeny, N. E. |
| Article Title: | Systemic or regional chemotherapy for liver metastases from colorectal cancer: Has the wheel stopped spinning? |
| Abstract: | The optimal management of patients with liver metastases from colorectal cancer is confounded by the large number of options available. In addition to ablative therapy (surgery, cryosurgery, radiofrequency ablation, etc.), chemotherapy plays a key role in the management of these patients. With more effective systemic therapy, some commentators have questioned the role of intra-arterial chemotherapy. However, a careful review of the literature, as well as ongoing research efforts, suggest that this approach remains an important option for patients and physicians to consider in appropriately selected patients for both first- and second-line therapy in advanced disease as well as for adjuvant therapy following resection of liver metastases. Copyright © 2004 Jones and Bartlett Publishers, Inc. |
| Keywords: | survival; cancer chemotherapy; survival analysis; clinical trial; review; patient selection; systemic therapy; antineoplastic agents; liver neoplasms; adjuvant therapy; chemotherapy, adjuvant; antineoplastic agent; colorectal cancer; metastasis; pathology; colorectal neoplasms; liver metastasis; colorectal tumor; adjuvant chemotherapy; liver tumor; radiofrequency ablation; clinical trials; cryosurgery; intra-arterial chemotherapy; humans; human; priority journal |
| Journal Title: | The Cancer Journal |
| Volume: | 10 |
| Issue: | 5 |
| ISSN: | 1528-9117 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2004-09-01 |
| Start Page: | 271 |
| End Page: | 279 |
| Language: | English |
| DOI: | 10.1097/00130404-200409000-00001 |
| PROVIDER: | scopus |
| PUBMED: | 15530253 |
| DOI/URL: | |
| Notes: | Cancer J. -- Cited By (since 1996):4 -- Export Date: 16 June 2014 -- CODEN: CAJOC -- Source: Scopus |
