Understanding erectile dysfunction medication preference studies Journal Article
| Author: | Mulhall, J. P. |
| Article Title: | Understanding erectile dysfunction medication preference studies |
| Abstract: | Purpose of review: The existence of three phosphodiesterase 5 inhibitors has resulted in an increase in the marketing of the drugs. This has led to a shift in focus from scientifically rigorous endpoints such as efficacy and adverse event profiles to patient preference. Recent findings: Although no consensus currently exists as to the correct methodology for preference studies, some basic guidelines should be adhered to, including: (1) the double-blinding of drug administration; (2) non-biased drug administration instructions; (3) an adequately conducted crossover study; (4) comparison of equivalent doses; (5) standardized preference assessment; (6) declaration of patient demographics; and (7) rigorous statistical analysis. These factors are discussed in the light of the three published preference studies. Summary: In the final analysis, it is unclear to this author how preference studies impact upon clinician decision-making when confronted by a patient with erectile dysfunction. |
| Keywords: | patient satisfaction; review; drug efficacy; side effect; physician's practice patterns; medical decision making; practice guideline; disease severity; statistical analysis; data interpretation, statistical; comorbidity; erectile dysfunction; phosphodiesterase v inhibitor; sildenafil; tadalafil; vardenafil; phosphodiesterase inhibitors; impotence; clinical trials; penis erection; drug choice; cross-over studies; drug marketing; pharmacotherapy; hardness; preference; humans; human; male; priority journal; drug trials; taste preference |
| Journal Title: | Current Opinion in Urology |
| Volume: | 14 |
| Issue: | 6 |
| ISSN: | 0963-0643 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2004-11-01 |
| Start Page: | 367 |
| End Page: | 373 |
| Language: | English |
| DOI: | 10.1097/00042307-200411000-00013 |
| PROVIDER: | scopus |
| PUBMED: | 15626881 |
| DOI/URL: | |
| Notes: | Curr. Opin. Urol. -- Cited By (since 1996):25 -- Export Date: 16 June 2014 -- CODEN: CUOUE -- Source: Scopus |
