On the reach of chemical synthesis: Creation of a mini-pipeline from an academic laboratory Journal Article

  


Authors: Wilson, R. M.; Danishefsky, S. J.
Article Title: On the reach of chemical synthesis: Creation of a mini-pipeline from an academic laboratory
Abstract: Successful journey: This retrospective Review describes investigations into the total synthesis and evaluation of biologically active small molecules (such as iso-fludelone; see structure), as well as the development of a program directed toward the chemical synthesis of therapeutically relevant larger molecules, including the glycoprotein erythropoietin. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Keywords: drug discovery; total synthesis; synthesis (chemical); carbohydrates; chemical synthesis; vaccines; small molecules; natural products; drug products; academic laboratory; fludelone
Journal Title: Angewandte Chemie - International Edition
Volume: 49
Issue: 35
ISSN: 1433-7851
Publisher: Wiley Blackwell  
Date Published: 2010-08-16
Start Page: 6032
End Page: 6056
Language: English
DOI: 10.1002/anie.201000775
PROVIDER: scopus
PUBMED: 20661969
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-77956034361&partnerID=40&md5=7c2c59ad6a3cc5387d807a3086791595
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 20 April 2011" - "CODEN: ACIEA" - "Source: Scopus"
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MSK Authors
  1. Samuel J Danishefsky
    539 Danishefsky
  2. Rebecca Wilson
    17 Wilson
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