Fatal pulmonary complications after arterial embolization with 40-120- micro m tris-acryl gelatin microspheres Journal Article


Author: Brown, K. T.
Article Title: Fatal pulmonary complications after arterial embolization with 40-120- micro m tris-acryl gelatin microspheres
Abstract: Hepatic arterial embolization is a recognized method of treating primary malignancies and some secondary hepatic malignancies. Particle embolization alone has been shown to be safe and effective and is routinely performed for hypervascular tumors. Tris-acryl gelatin microspheres have been widely acclaimed for their ease of delivery and uniform size, allowing for accurate targeting of particular end arteries. There have been three deaths at the author's institution related to respiratory compromise since the 40-120-μm particles became available 31 months ago. These complications were never observed with larger tris-acryl gelatin microspheres or polyvinyl alcohol particles. This is an unusual and serious complication of which interventionalists performing embolotherapy need to be aware.
Keywords: aged; case report; artificial embolism; liver cell carcinoma; carcinoma, hepatocellular; liver neoplasms; tumor vascularization; hypoxemia; embolization, therapeutic; particle size; hepatic artery; methylamines; pulmonary hypertension; hypertension, pulmonary; polyvinyl alcohol; microsphere; gelatin; microspheres; acrylates; respiratory arrest; humans; human; male; priority journal; article; anoxemia
Journal Title: Journal of Vascular and Interventional Radiology
Volume: 15
Issue: 2 Pt.1
ISSN: 1051-0443
Publisher: Elsevier Science, Inc.  
Date Published: 2004-02-01
Start Page: 197
End Page: 200
Language: English
PROVIDER: scopus
PUBMED: 14963189
DOI: 10.1097/01.RVI.0000109400.52762.1F
DOI/URL:
Notes: J. Vasc. Intervent. Radiol. -- Cited By (since 1996):46 -- Export Date: 16 June 2014 -- CODEN: JVIRE C2 - 14963189 -- Source: Scopus
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  1. Karen T Brown
    178 Brown