Brain metastases in hepatoblastoma Journal Article


Authors: Begemann, M.; Trippett, T. M.; Lis, E.; Antunes, N. L.
Article Title: Brain metastases in hepatoblastoma
Abstract: Brain metastases from hepatoblastomas are rare. We report a 2-year-old male who developed multiple hemorrhagic intracranial metastases. Previous reports indicate that brain metastases are an almost uniformly fatal complication of hepatoblastoma, although one long-term survivor has been described. In a child with known hepatoblastoma, the development of neurologic signs or symptoms should lead to the performance of a brain imaging study to exclude the possibility of intracranial extension of the disease. © 2004 by Elsevier Inc. All rights reserved.
Keywords: cancer chemotherapy; child; human tissue; treatment outcome; child, preschool; thalidomide; clinical feature; case report; cisplatin; doxorubicin; fluorouracil; cancer combination chemotherapy; liver neoplasms; cancer radiotherapy; topotecan; brain neoplasms; follow-up studies; neoplasm staging; carboplatin; computer assisted tomography; diagnosis, differential; etoposide; thoracotomy; lung neoplasms; tomography, x-ray computed; cyclophosphamide; dexamethasone; vincristine; tumor biopsy; biopsy; medical examination; irinotecan; lung metastasis; liver; infant; disease progression; brain metastasis; liver surgery; fatal outcome; liver biopsy; exatecan; brain hemorrhage; cerebral hemorrhage; parietal lobe; occipital lobe; hepatoblastoma; humans; human; male; priority journal; article
Journal Title: Pediatric Neurology
Volume: 30
Issue: 4
ISSN: 0887-8994
Publisher: Elsevier Inc.  
Date Published: 2004-04-01
Start Page: 295
End Page: 297
Language: English
DOI: 10.1016/j.pediatrneurol.2003.10.014
PROVIDER: scopus
PUBMED: 15087112
DOI/URL:
Notes: Pediatr. Neurol. -- Cited By (since 1996):6 -- Export Date: 16 June 2014 -- CODEN: PNEUE -- Source: Scopus
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  1. Tanya M Trippett
    126 Trippett
  2. Eric Lis
    138 Lis
  3. Nuno L Antunes
    22 Antunes