Up-regulation of GADD34 mediates the synergistic anticancer activity of mitomycin C and a γ134.5 deleted oncolytic herpes virus (G207) Journal Article


Authors: Bennett, J. J.; Adusumilli, P.; Petrowsky, H.; Burt, B. M.; Roberts, G.; Delman, K. A.; Zager, J. S.; Chou, T. C.; Fong, Y.
Article Title: Up-regulation of GADD34 mediates the synergistic anticancer activity of mitomycin C and a γ134.5 deleted oncolytic herpes virus (G207)
Keywords: cancer chemotherapy; controlled study; unclassified drug; human cell; gene deletion; genetics; drug potentiation; multimodality cancer therapy; nonhuman; antineoplastic agents; combined modality therapy; antineoplastic agent; proteins; cell cycle protein; animal cell; mouse; animal; metabolism; animals; cell cycle proteins; mice; cell death; gene; dna repair; animal experiment; animal model; protein; small interfering rna; rna, small interfering; gene product; antineoplastic activity; cytotoxicity; in vitro study; drug effect; pathology; cell line, tumor; physiology; virology; animalia; drug synergism; drug mechanism; messenger rna; rna, messenger; tumor cell line; oncolytic virus; herpesviridae; simplexvirus; stomach cancer; gene control; herpesvirus 1, human; upregulation; virus load; pathogenicity; up-regulation; mitomycin; herpes simplex virus 1; stomach neoplasms; concentration response; stomach tumor; carcinomatosis; antigens, differentiation; differentiation antigen; northern blotting; g 207; herpes virus infection; herpesviridae infections; virulence; viral gene therapy; human herpesvirus 1; humans; human; priority journal; article; ppp1r15a protein, human; ppp1r15a protein, mouse; gadd34 gene
Journal Title: FASEB Journal
Volume: 18
Issue: 9
ISSN: 0892-6638
Publisher: Federation of American Societies for Experimental Biology  
Date Published: 2004-06-01
Start Page: 1001
End Page: 1003
Language: English
DOI: 10.1096/fj.02-1080fje
PROVIDER: scopus
PUBMED: 15059970
DOI/URL:
Notes: FASEB J. -- Cited By (since 1996):47 -- Export Date: 16 June 2014 -- CODEN: FAJOE -- Source: Scopus
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MSK Authors
  1. Keith Delman
    19 Delman
  2. Jonathan Zager
    15 Zager
  3. Bryan M Burt
    18 Burt
  4. Joseph J Bennett
    19 Bennett
  5. Yuman Fong
    775 Fong
  6. Ting-Chao Chou
    319 Chou