Gastrointestinal adenocarcinoma arising in a mature cystic teratoma of the ovary Journal Article

Authors: Levine, D. A.; Villella, J. A.; Poynor, E. A.; Soslow, R. A.
Article Title: Gastrointestinal adenocarcinoma arising in a mature cystic teratoma of the ovary
Abstract: Background. Mature cystic teratoma of the ovary (MCTO) is the most common ovarian germ cell neoplasm and is usually diagnosed in early adulthood. Malignant transformation is rare, occurring in approximately 2% of all cases. Though malignant transformation can occur from any of the embryonic germ layers, the most common malignancy arising in these otherwise benign tumors is squamous cell carcinoma. Case. We present a patient with a MCTO where malignant transformation of gastrointestinal epithelium resulted in moderately differentiated adenocarcinoma. After 3 years of follow-up, she remains free of disease. Conclusion. Although gastrointestinal epithelium is often found in MCTOs, adenocarcinoma arising from this cell type is uncommon. This is the third reported case of adenocarcinoma arising in gastrointestinal epithelium of a MCTO. © 2004 Elsevier Inc. All rights reserved.
Keywords: adult; human tissue; treatment outcome; surgical technique; clinical feature; disease course; histopathology; anamnesis; case report; follow up; adenocarcinoma; ovarian cancer; ovarian neoplasms; cell transformation, neoplastic; gastrointestinal neoplasms; health status; teratoma; physical examination; ovary teratoma; malignant transformation; dermoid cyst; gastrointestinal carcinoma; intestine epithelium; stomach epithelium; humans; human; female; priority journal; article; cystic teratoma of the ovary; mature cystic teratoma of the ovary
Journal Title: Gynecologic Oncology
Volume: 94
Issue: 2
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2004-08-01
Start Page: 597
End Page: 599
Language: English
DOI: 10.1016/j.ygyno.2004.05.045
PROVIDER: scopus
PUBMED: 15297213
Notes: Gynecol. Oncol. -- Cited By (since 1996):15 -- Export Date: 16 June 2014 -- CODEN: GYNOA -- Source: Scopus
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MSK Authors
  1. Elizabeth Poynor
    32 Poynor
  2. Douglas A Levine
    360 Levine
  3. Robert Soslow
    670 Soslow