Clinical significance of unexplained abnormal focal FDG uptake in the abdomen during whole-body PET Journal Article

  


Authors: Pandit-Taskar, N.; Schöder, H.; Gonen, M.; Larson, S. M.; Yeung, H. W. D.
Article Title: Clinical significance of unexplained abnormal focal FDG uptake in the abdomen during whole-body PET
Abstract: OBJECTIVE. FDG PET is frequently used as part of the diagnostic workup in cancer patients. Visualization of radiotracer-avid foci suggests the presence of malignant disease. Unexplained focal FDG accumulation in the abdomen is sometimes noted, but the clinical significance of this finding is unknown. Therefore, we followed cases with unexplained focal abdominal FDG uptake found incidentally on whole-body scans to define the cause and clinical significance of this finding. CONCLUSION. Unexplained focal abdominal FDG uptake is an unusual finding with causes that include malignant and benign processes. Among the 14 cases with definitive diagnoses, seven were adenomas, which is a premalignant condition, and five (35.7%) were malignant. Therefore, although rare, unexplained focal abdominal FDG uptake should not be ignored and further diagnostic workup is warranted. © American Roentgen Ray Society.
Keywords: controlled study; aged; middle aged; major clinical study; pathophysiology; positron emission tomography; radiopharmaceuticals; neoplasm; neoplasms; diagnosis, differential; differential diagnosis; diagnostic imaging; abdomen; diagnostic agent; fluorodeoxyglucose f 18; computer assisted emission tomography; fluorodeoxyglucose f18; radiopharmaceutical agent; scintiscanning; malignant neoplastic disease; tracer; fluorodeoxyglucose; tomography, emission-computed; whole body scintiscanning; cancer; humans; human; male; female; priority journal; article
Journal Title: American Journal of Roentgenology
Volume: 183
Issue: 4
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2004-10-01
Start Page: 1143
End Page: 1147
Language: English
PROVIDER: scopus
PUBMED: 15385321
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-7944236674&partnerID=40&md5=2f41c91a4ab622e435f3a03b0d30852d
Notes: Am. J. Roentgenol. -- Cited By (since 1996):37 -- Export Date: 16 June 2014 -- CODEN: AJROA C2 - 15385321 -- Source: Scopus
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MSK Authors
  1. Henry W D Yeung
    126 Yeung
  2. Mithat Gonen
    1032 Gonen
  3. Heiko Schoder
    551 Schoder
  4. Neeta Pandit-Taskar
    344 Pandit-Taskar
  5. Steven M Larson
    959 Larson
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