TAME-Hex A - A novel bifunctional chelating agent for radioimmunoimaging Journal Article


Authors: Arslantas, E.; Smith-Jones, P. M.; Ritter, G.; Schmidt, R. R.
Article Title: TAME-Hex A - A novel bifunctional chelating agent for radioimmunoimaging
Abstract: Two novel (bifunctional) chelating agents, TAME-Hex A and B, which are polyaminopolycarboxylic acids based on the tripodal TAME [tris(aminomethyl) ethane] structure, have been designed and synthesized. The chelators show very good stability with gallium(III) ions and thus are highly effective candidates for use in radioimmunoimaging (RII), especially in positron emission tomography (PET). © Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
Keywords: unclassified drug; positron emission tomography; imaging; chelate; polymer; synthesis; chelating agents; carboxylic acid derivative; molecular stability; gallium; chelating agent; radioimmunoimaging; new drug; article; gallium chelate; tame derivative; ethane; polyaminocarboxylic acid derivative; tris(aminomethyl)ethane; tris(aminomethyl)ethane n,n,n',n',n',n'' hexaacetic acid
Journal Title: European Journal of Organic Chemistry
Volume: 2004
Issue: 19
ISSN: 1434-193X
Publisher: Wiley V C H Verlag Gmbh  
Date Published: 2004-01-01
Start Page: 3979
End Page: 3984
Language: English
DOI: 10.1002/ejoc.200400224
PROVIDER: scopus
DOI/URL:
Notes: Eur. J. Org. Chem. -- Cited By (since 1996):15 -- Export Date: 16 June 2014 -- CODEN: EJOCF -- Source: Scopus
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