The use of colorectal stents for palliation of large-bowel obstruction due to recurrent gynecologic cancer Journal Article

Authors: Pothuri, B.; Guirguis, A.; Gerdes, H.; Barakat, R. R.; Chi, D. S.
Article Title: The use of colorectal stents for palliation of large-bowel obstruction due to recurrent gynecologic cancer
Abstract: Acute large-bowel obstruction (LBO) is considered a surgical emergency. In gynecologic oncology patients with LBO due to recurrent tumor, surgery has been the standard treatment. However, operative intervention has significant associated morbidity and mortality. Recent reports have addressed the use of colorectal stents for the treatment of colonic malignancies. We are reporting our experience with colorectal stents in gynecologic oncology patients. We reviewed the records of all patients who underwent colorectal stent placement for palliation of LBO due to recurrent gynecologic malignancy from August 2001 to January 2003. Six patients were identified; five patients had recurrent ovarian cancer and one had recurrent endometrial cancer. The mean age of the six patients at the time of stent placement was 51.5 years (range, 22-83 years).The length of LBO ranged from 2 to 10 cm. Two patients had a lumen of 1 to 2 mm before stent placement, while the other four had a complete obstruction and needed balloon dilatation before the deployment of the stent. Four (67%) of six patients had immediate relief, with passage of stool and flatus noted at the time of the colorectal stent placement. Stent placement failed to relieve the LBO in two patients (33%); these patients went on to receive colostomies. Of the four patients who had successful stent placement, the mean survival after stent placement was 120 days. One patient had a contained sigmoid bowel perforation noted 12 days after stent placement, which resolved with conservative measures. Colonic stents appear to be a useful option in the management of patients with LBO due to recurrent gynecologic malignancy. © 2004 Elsevier Inc. All rights reserved.
Keywords: adult; clinical article; controlled study; treatment outcome; aged; aged, 80 and over; middle aged; survival rate; treatment failure; retrospective studies; recurrent cancer; endometrial neoplasms; endometrium cancer; cancer palliative therapy; palliative care; ovarian neoplasms; ovary cancer; neoplasm recurrence, local; experience; medical record; intestine perforation; recurrent gynecologic cancer; intestine obstruction; intestinal obstruction; flatulence; gynecologic cancer; feces; digestive system surgical procedures; stents; palliation; colostomy; balloon dilatation; large-bowel obstruction; colorectal stents; colon, sigmoid; sigmoid; drug eluting stent; humans; human; female; priority journal; article
Journal Title: Gynecologic Oncology
Volume: 95
Issue: 3
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2004-12-01
Start Page: 513
End Page: 517
Language: English
DOI: 10.1016/j.ygyno.2004.07.064
PROVIDER: scopus
PUBMED: 15581955
Notes: Gynecol. Oncol. -- Cited By (since 1996):26 -- Export Date: 16 June 2014 -- CODEN: GYNOA -- Source: Scopus
Citation Impact
MSK Authors
  1. Hans Gerdes
    164 Gerdes
  2. Richard R Barakat
    629 Barakat
  3. Dennis S Chi
    619 Chi
  4. Bhavana Pothuri
    14 Pothuri