Analysis of postoperative complications of open partial laryngectomy Journal Article
| Authors: | Ganly, I.; Patel, S. G.; Matsuo, J. M. S.; Singh, B.; Kraus, D. H.; Boyle, J.; Wong, R.; Shaha, A. R.; Shah, J. P. |
| Article Title: | Analysis of postoperative complications of open partial laryngectomy |
| Abstract: | Background. The objective of this study was to report the incidence of postoperative complications for partial laryngectomy and to identify patient- and tumor-related factors predictive of postoperative complications. Methods. A total of 150 patients who had a partial laryngectomy were identified from an existing database of 662 patients treated for squamous cell carcinoma of the larynx from 1984 to 1998. Postoperative complications were recorded and categorized into local, swallowing, airway, and systemic complications. Patient- and tumor-related predictors of complications were identified by univariate and multivariate analyses. Results. There was no postoperative mortality. Twenty percent of patients developed a postoperative complication following partial laryngectomy. Local complications were the most frequent complication and occurred in 17 (11%) patients. Laryngocutaneous fistula occurred in 6 (4%) patients. Multivariate analysis showed that prior radiation was an independent predictor of local complications and laryngocutaneous fistula with a 13-fold increase in relative risk for both. Conclusion. Partial laryngectomy following radiotherapy was more frequently associated with postoperative complications. Problems related to local wound healing, especially the development of laryngocutaneous fistula, constituted the most common postoperative complication in these patients. ©2008 Wiley Periodicals, Inc. |
| Keywords: | adult; aged; aged, 80 and over; middle aged; major clinical study; laryngectomy; larynx carcinoma; neck dissection; salvage therapy; skin fistula; squamous cell carcinoma; carcinoma, squamous cell; cutaneous fistula; fistula; laryngeal neoplasms; cancer radiotherapy; radiotherapy, adjuvant; cancer staging; tumor localization; kidney disease; lung disease; incidence; smoking; data base; risk factor; postoperative complication; wound healing; wound; dysphagia; length of stay; correlation coefficient; heart infarction; stoma; bile leakage; urinary tract infection; comorbidity; complications; multivariate analysis; alcohol consumption; wound infection; univariate analysis; ear nose throat surgery; laryngeal diseases; laryngocutaneous fistula; partial laryngectomy; salvage; chyle; esophagus stricture; fisher exact test; glottis; metabolic disorder; trachea disease; wound dehiscence |
| Journal Title: | Head & Neck |
| Volume: | 31 |
| Issue: | 3 |
| ISSN: | 1043-3074 |
| Publisher: | John Wiley & Sons, Inc. |
| Date Published: | 2009-03-01 |
| Start Page: | 338 |
| End Page: | 345 |
| Language: | English |
| DOI: | 10.1002/hed.20975 |
| PUBMED: | 19073010 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 3" - "Export Date: 30 November 2010" - "CODEN: HEANE" - "Source: Scopus" |
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